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EC 1.14.13.70 sterol 14-demethylase

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

obtusifoliol + 3 O2 + 3 NADPH + 3 H+ = 4alpha-methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + formate + 3 NADP+ + 3 H2O

Reaction(s) (KEGG)

R03690 [Fig]4,4',14alpha-Trimethyl-5alpha-cholesta-8,24-dien-3beta-ol + O2 + NADPH + H+ <=>14-Demethyllanosterol + Formate + NADP+
R05640 [Fig]4,4',14alpha-Trimethyl-5alpha-cholesta-8,24-dien-3beta-ol + 3 O2 + 3 NADPH + 3 H+ <=>4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + Formate + 3 NADP+ + 3 H2O
R05731 [Fig]4alpha,14alpha-Dimethyl-24-methylene-5alpha-cholesta-8-en-3beta-ol + 3 O2 + 3 NADPH + 3 H+ <=>4alpha-Methyl-5alpha-ergosta-8,14,24(28)-trien-3beta-ol + Formate + 3 NADP+ + 3 H2O

BiSSCat v1.06.20 http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.