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FGROUP
SUBSTRUCTURE
compound
enzyme
Multiple
Lanosterol,NADPH:oxygen oxidoreductase (14-methyl cleaving)
Database Link
KEGG
1.14.13.70
sterol 14-demethylase
Equation
Lanosterol + 3 Oxygen + 3 NADPH + 3 H+ <=>4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + Formate + 3NADP+ + 3 H2O
Equation (left side)
4,4',14alpha-Trimethyl-5alpha-cholesta-8,24-dien-3beta-ol
O2
NADPH
H+
Equation (right side)
4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol
Formate
NADP+
H2O
BiSSCat v1.06.20
http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.