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(Deoxyribonucleotide)n:(Deoxyribonucleotide)m ligase (AMP-forming,NMN-forming)

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KEGG 6.5.1.2 DNA ligase (NAD+)

Equation

NAD+ + DNA(n) + DNA(m) <=> AMP + Nicotinamide D-ribonucleotide +DNA(n+m)

Equation (left side)

NAD+
(Deoxyribonucleotide)m
(Deoxyribonucleotide)m

Equation (right side)

5'-AMP
NMN
(Deoxyribonucleotide)m

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Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.