BiSSCat: glutamate-ammonia ligase

EC 6.3.1.2 glutamate-ammonia ligase

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine

Reaction(s) (KEGG)

R05028	[Fig]	ATP + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L- alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + Ammonia	<=>	ADP + Orthophosphate + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L- alanyl-D-glutaminyl-L-lysyl-D-alanyl-D-alanine
R05030	[Fig]	ATP + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L- alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine + Ammonia	<=>	ADP + Orthophosphate + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L- alanyl-D-isoglutaminyl-L-lysyl-D-alanyl-D-alanine
R05033	[Fig]	ATP + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L- alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + Ammonia	<=>	ADP + Orthophosphate + Undecaprenyl-diphospho-N-acetylmuramoyl-(N-acetylglucosamine)-L- alanyl-D-glutaminyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine
R00253	[Fig]	ATP + L-Glutamate + Ammonia	<=>	ADP + Orthophosphate + L-Glutamine

Inhibitor(s)

L-Methionine sulfoximine

2S,5S-Methionine sulfoximine

3-(Phosphoacetylamido)-L-alanine

L-2-Amino-4-(hydroxymethylphosphinyl)butanoate

BiSSCat v1.06.20 http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.