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Home Help FGROUP SUBSTRUCTURE compound enzyme Multiple

EC 3.4.24.80 membrane-type matrix metalloproteinase-1

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

Endopeptidase activity. Activates progelatinase A by cleavage of the propeptide at Asn37-|-Leu. Other bonds hydrolysed include Gly35-|-Ile in the propeptide of collagenase 3, and Asn341-|-Phe, Asp441-|-Leu and Gln354-|-Thr in the aggrecan interglobular


BiSSCat v1.06.20 http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.