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Home Help FGROUP SUBSTRUCTURE compound enzyme Multiple

EC 3.4.24.7 interstitial collagenase

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

Cleavage of the triple helix of collagen at about three-quarters of the length of the molecule from the N-terminus, at Gly775-|-Ile in the alpha1(I) chain. Cleaves synthetic substrates and alpha-macroglobulins at bonds where P1' is a hydrophobic residue

Cofactor(s)

Zinc

BiSSCat v1.06.20 http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.