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Home Help FGROUP SUBSTRUCTURE compound enzyme Multiple

EC 3.4.24.55 pitrilysin

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

Preferential cleavage of -Tyr16-|- Leu- and -Phe25-|- Tyr-bonds of oxidized insulin B chain. Also acts on other substrates of less than 7 kDa such as insulin and glucagon

Cofactor(s)

Zinc

Inhibitor(s)

Chelating agents
1,10-Phenanthroline

BiSSCat v1.06.20 http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.