Preference for hydrophobic residues at P1 and P1'. Action on the B chain of insulin is generally similar to that of pepsin A, but it also cleaves Leu6-|-Cys(SO3H), Glu21-|-Arg and Asn3-|-Gln, although not Gln4-His
BiSSCat v1.06.20http://bisscat.org/ Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin. Science Foundation of Ireland is gratefully acknowledged.