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Home Help FGROUP SUBSTRUCTURE compound enzyme Multiple

EC 3.4.22.36 caspase-1

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

Release of interleukin 1beta by specific cleavage at -Asp116-|-Ala- and -Asp27-|-Gly- bonds in precursor. Also hydrolyses the small-molecule substrate, Ac-Tyr-Val-Ala-Asp-|-NHMec


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Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.