Fully activates human clotting factor V by a single cleavage at the Trp-Tyr-Leu-Arg1545-|-Ser-Asn-Asn-Gly bond. Cattle, but not rabbit, factor V is cleaved, and no other proteins of the clotting system are attacked. Esterase activity is observed on Bz-Arg- OEt and Tos-Arg- OMe, and amidase activity on Phe-pipecolyl-Arg-NHPhNO2
BiSSCat v1.06.20http://bisscat.org/ Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin. Science Foundation of Ireland is gratefully acknowledged.