Preferential cleavage of Arg-|- bonds in small molecule substrates. Highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|- or Leu-|-. The rat enzyme is unusual in liberating bradykinin directly from autologous kininogens by cleavage at two Arg-|- bonds
BiSSCat v1.06.20http://bisscat.org/ Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin. Science Foundation of Ireland is gratefully acknowledged.