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Home Help FGROUP SUBSTRUCTURE compound enzyme Multiple

EC 2.5.1.48 cystathionine gamma-synthase

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

O-succinyl-L-homoserine + L-cysteine = cystathionine + succinate

Reaction(s) (KEGG)

R04944 [Fig]O-Phosphorylhomoserine + Selenocysteine <=>Selenocystathionine + Orthophosphate
R04945 [Fig]O-Acetylhomoserine + Selenocysteine <=>Selenocystathionine + Acetate
R04946 [Fig]O-Succinylhomoserine + Selenocysteine <=>Selenocystathionine + Butanedionic acid
R01288 [Fig]O-Succinyl-L-homoserine + Sulfide <=>L-Homocysteine + Butanedionic acid
R00999 [Fig]O-Succinyl-L-homoserine + H2O <=>2-Ketobutyric acid + Butanedionic acid + Ammonia
R02508 [Fig]Cystathionine + Butanedionic acid <=>O-Succinyl-L-homoserine + L-Cysteine
R03260 [Fig]O-Succinyl-L-homoserine + L-Cysteine <=>L-Cystathionine + Butanedionic acid
R03132 [Fig]O-Acetyl-L-serine + Hyposulfite <=>S-Sulfo-L-cysteine + Acetate

Cofactor(s)

Pyridoxal 5'-phosphate

BiSSCat v1.06.20 http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.