BiSSCat Search in
Home Help FGROUP SUBSTRUCTURE compound enzyme Multiple

EC 2.3.1.85 fatty-acid synthase

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = a long-chain fatty acid + (n+1) CoA + n CO2 + 2n NADP+

Reaction(s) (KEGG)

R04566 [Fig](3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] + NADP+ <=>3-Oxotetradecanoyl-[acp] + NADPH
R04568 [Fig](3R)-3-Hydroxytetradecanoyl-[acyl-carrier protein] <=>trans-Tetradec-2-enoyl-[acp] + H2O
R04543 [Fig](3R)-3-Hydroxyhexadecanoyl-[acyl-carrier protein] + NADP+ <=>3-Oxohexadecanoyl-[acp] + NADPH
R04544 [Fig](3R)-3-Hydroxyhexadecanoyl-[acyl-carrier protein] <=>trans-Hexadec-2-enoyl-[acp] + H2O
R04960 [Fig]Octanoyl-[acp] + Malonyl-[acyl-carrier protein] <=>3-Oxodecanoyl-[acp] + CO2 + ACP
R04962 [Fig]Decanoyl-[acp] + NADP+ <=>trans-Dec-2-enoyl-[acp] + NADPH
R04963 [Fig]Decanoyl-[acp] + Malonyl-[acyl-carrier protein] <=>3-Oxododecanoyl-[acp] + CO2 + ACP
R04964 [Fig](R)-3-Hydroxydodecanoyl-[acp] + NADP+ <=>3-Oxododecanoyl-[acp] + NADPH
R04965 [Fig](R)-3-Hydroxydodecanoyl-[acp] <=>trans-Dodec-2-enoyl-[acp] + H2O
R04967 [Fig]Tetradecanoyl-[acp] + NADP+ <=>trans-Tetradec-2-enoyl-[acp] + NADPH
R04968 [Fig]Tetradecanoyl-[acp] + Malonyl-[acyl-carrier protein] <=>3-Oxohexadecanoyl-[acp] + CO2 + ACP
R04725 [Fig]Dodecanoyl-[acp] + NADP+ <=>trans-Dodec-2-enoyl-[acp] + NADPH + H+
R04726 [Fig]Dodecanoyl-[acp] + Malonyl-[acyl-carrier protein] <=>3-Oxotetradecanoyl-[acp] + CO2 + ACP
R01624 [Fig]Acetyl-CoA + ACP <=>CoA + Acetyl-[acyl-carrier protein]
R01626 [Fig]Malonyl-CoA + ACP <=>CoA + Malonyl-[acyl-carrier protein]
R04355 [Fig]Acetyl-[acyl-carrier protein] + Malonyl-[acyl-carrier protein] <=>Acetoacetyl-[acp] + CO2 + ACP
R04970 [Fig]Hexadecanoyl-[acp] + NADP+ <=>trans-Hexadec-2-enoyl-[acp] + NADPH
R04533 [Fig](3R)-3-Hydroxybutanoyl-[acyl-carrier protein] + NADP+ <=>Acetoacetyl-[acp] + NADPH
R04534 [Fig](3R)-3-Hydroxydecanoyl-[acyl-carrier protein] + NADP+ <=>3-Oxodecanoyl-[acp] + NADPH
R04535 [Fig](3R)-3-Hydroxydecanoyl-[acyl-carrier protein] <=>trans-Dec-2-enoyl-[acp] + H2O
R04536 [Fig](3R)-3-Hydroxyoctanoyl-[acyl-carrier protein] + NADP+ <=>3-Oxooctanoyl-[acp] + NADPH
R04537 [Fig](3R)-3-Hydroxyoctanoyl-[acyl-carrier protein] <=>2-Octenoyl-[acyl-carrier protein] + H2O
R04952 [Fig]Butyryl-[acp] + Malonyl-[acyl-carrier protein] <=>3-Oxohexanoyl-[acp] + CO2 + ACP
R04953 [Fig](R)-3-Hydroxyhexanoyl-[acp] + NADP+ <=>3-Oxohexanoyl-[acp] + NADPH
R04954 [Fig](R)-3-Hydroxyhexanoyl-[acp] <=>trans-Hex-2-enoyl-[acp] + H2O
R04956 [Fig]Hexanoyl-[acp] + NADP+ <=>trans-Hex-2-enoyl-[acp] + NADPH
R04957 [Fig]Hexanoyl-[acp] + Malonyl-[acyl-carrier protein] <=>3-Oxooctanoyl-[acp] + CO2 + ACP
R04959 [Fig]Octanoyl-[acp] + NADP+ <=>2-Octenoyl-[acyl-carrier protein] + NADPH
R05188 [Fig]Acetyl-CoA + n Malonyl-CoA + 2n NADPH <=>Higher fatty acid + n CO2 + 2n NADP+ + (n+1) CoA
R01706 [Fig]Hexadecanoyl-[acp] + H2O <=>ACP + Cetylic acid

BiSSCat v1.06.20 http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.