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Home Help FGROUP SUBSTRUCTURE compound enzyme Multiple

EC 1.5.1.20 methylenetetrahydrofolate reductase (NADPH)

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+

Reaction(s) (KEGG)

R01222 [Fig]5,10-Methylene-THF + FADH2 <=>5-Methyltetrahydrofolate + FAD
R01224 [Fig]5-Methyltetrahydrofolate + NADP+ <=>5,10-Methylene-THF + NADPH + H+

Cofactor(s)

FAD
BiSSCat v1.06.20 http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.