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Home Help FGROUP SUBSTRUCTURE compound enzyme Multiple

EC 1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

3-methyl-2-oxobutanoate + lipoyllysine = S-(2-methylpropanoyl)dihydrolipoyllysine + CO2

Reaction(s) (KEGG)

R04225 [Fig]2-Oxo-3-methylvalerate + Lipoamide <=>S-(2-Methylbutanoyl)-dihydrolipoamide + CO2
R01701 [Fig]alpha-Ketovaline + Lipoamide <=>S-(2-Methylpropanoyl)-dihydrolipoamide + CO2
R01702 [Fig]2-Oxoisocaproate + Lipoamide <=>S-(3-Methylbutanoyl)-dihydrolipoamide + CO2

Cofactor(s)

Thiamine diphosphate
BiSSCat v1.06.20 http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.