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Home Help FGROUP SUBSTRUCTURE compound enzyme Multiple

EC 1.17.4.2 ribonucleoside-triphosphate reductase

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin

Reaction(s) (KEGG)

R02014 [Fig]dATP + Oxidized thioredoxin + H2O <=>ATP + Reduced thioredoxin
R04315 [Fig]2'-Deoxyribonucleoside triphosphate + Oxidized thioredoxin + H2O <=>Ribonucleoside triphosphate + Reduced thioredoxin
R02020 [Fig]2'-Deoxyguanosine 5'-triphosphate + Oxidized thioredoxin + H2O <=>GTP + Reduced thioredoxin
R02022 [Fig]2'-Deoxycytidine 5'-triphosphate + Oxidized thioredoxin + H2O <=>CTP + Reduced thioredoxin
R02023 [Fig]2'-Deoxyuridine 5'-triphosphate + Oxidized thioredoxin + H2O <=>UTP + Reduced thioredoxin

Cofactor(s)

ATP
Iron
Cobalt
Cobalamin coenzyme
BiSSCat v1.06.20 http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.