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Home Help FGROUP SUBSTRUCTURE compound enzyme Multiple

EC 1.17.4.1 ribonucleoside-diphosphate reductase

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin

Reaction(s) (KEGG)

R02017 [Fig]2'-Deoxyadenosine 5'-diphosphate + Oxidized thioredoxin + H2O <=>Reduced thioredoxin + ADP
R02018 [Fig]2'-Deoxyuridine 5'-diphosphate + Oxidized thioredoxin + H2O <=>Reduced thioredoxin + UDP
R02019 [Fig]2'-Deoxyguanosine 5'-diphosphate + Oxidized thioredoxin + H2O <=>GDP + Reduced thioredoxin
R02024 [Fig]2'-Deoxycytidine 5'-diphosphate + Oxidized thioredoxin + H2O <=>Reduced thioredoxin + CDP
R04294 [Fig]2'-Deoxyribonucleoside diphosphate + Oxidized thioredoxin + H2O <=>Ribonucleoside diphosphate + Reduced thioredoxin

Cofactor(s)

ATP
Iron
BiSSCat v1.06.20 http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.