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Home Help FGROUP SUBSTRUCTURE compound enzyme Multiple

EC 1.14.99.9 steroid 17alpha-monooxygenase

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

a steroid + AH2 + O2 = a 17alpha-hydroxysteroid + A + H2O

Reaction(s) (KEGG)

R04852 [Fig]21-Deoxycortisol + Acceptor + H2O <=>11beta-Hydroxyprogesterone + Reduced acceptor + O2
R04853 [Fig]20alpha-Hydroxycholesterol + NADPH + H+ + O2 <=>17alpha,20alpha-Dihydroxycholesterol + NADP+ + H2O
R03783 [Fig]3beta-Hydroxypregn-5-en-20-one + Reduced acceptor + O2 <=>17alpha-Hydroxypregnenolone + Acceptor + H2O
R02211 [Fig]4-Pregnene-3,20-dione + Reduced acceptor + O2 <=>17alpha-Hydroxy-4-pregnene-3,20-dione + Acceptor + H2O
R02131 [Fig]Steroid + Reduced acceptor + O2 <=>17-alpha-Hydroxysteroid + Acceptor + H2O

Cofactor(s)

NADH
NADPH
Haem
BiSSCat v1.06.20 http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.