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Home Help FGROUP SUBSTRUCTURE compound enzyme Multiple

EC 1.14.99.10 steroid 21-monooxygenase

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

a steroid + AH2 + O2 = a 21-hydroxysteroid + A + H2O

Reaction(s) (KEGG)

R04675 [Fig]17alpha-Hydroxypregnenolone + NADPH + H+ + O2 <=>17alpha,21-Dihydroxypregnenolone + NADP+ + H2O
R03784 [Fig]3beta-Hydroxypregn-5-en-20-one + Reduced acceptor + O2 <=>21-Hydroxypregnenolone + Acceptor + H2O
R03326 [Fig]17alpha-Hydroxy-4-pregnene-3,20-dione + Reduced acceptor + O2 <=>11-Deoxycortisol + Acceptor + H2O
R02213 [Fig]4-Pregnene-3,20-dione + Reduced acceptor + O2 <=>11-Deoxycorticosterone + Acceptor + H2O
R02838 [Fig]21-Deoxycortisol + Reduced acceptor + O2 <=>11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione + Acceptor + H2O
R03849 [Fig]11beta-Hydroxyprogesterone + Reduced acceptor + O2 <=>11beta,21-Dihydroxy-4-pregnene-3,20-dione + Acceptor + H2O
R02130 [Fig]Steroid + Reduced acceptor + O2 <=>21-Hydroxysteroid + Acceptor + H2O

Cofactor(s)

Haem
Flavin
BiSSCat v1.06.20 http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.