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Home Help FGROUP SUBSTRUCTURE compound enzyme Multiple

EC 1.14.16.4 tryptophan 5-monooxygenase

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4a-hydroxytetrahydrobiopterin

Reaction(s) (KEGG)

R01814 [Fig]2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + L-Tryptophan + O2 <=>5-Hydroxy-L-tryptophan + 6,7-Dihydrobiopterin + H2O

Cofactor(s)

Iron

BiSSCat v1.06.20 http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.