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Home Help FGROUP SUBSTRUCTURE compound enzyme Multiple

EC 1.14.13.41 tyrosine N-monooxygenase

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

(1) L-tyrosine + O2 + NADPH + H+ = N-hydroxy-L-tyrosine + NADP+ + H2O; (2) N-hydroxy-L-tyrosine + O2 + NADPH + H+ = N,N-dihydroxy-L-tyrosine + NADP+ + H2O; (3) N,N-dihydroxy-L-tyrosine = (Z)- + CO2 + H2O

Reaction(s) (KEGG)

R01260 [Fig]L-Amino acid + O2 + NADPH <=>N-Hydroxy-amino acid + NADP+ + H2O
R04460 [Fig]N-Hydroxy-L-tyrosine + O2 + NADPH + 2 H+ <=>(Z)-4-Hydroxyphenylacetaldehyde-oxime + NADP+ + 2 H2O + CO2
R00730 [Fig]L-Tyrosine + O2 + NADPH + H+ <=>N-Hydroxy-L-tyrosine + NADP+ + H2O

Cofactor(s)

Haem
BiSSCat v1.06.20 http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.