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Home Help FGROUP SUBSTRUCTURE compound enzyme Multiple

EC 1.1.4.1 vitamin-K-epoxide reductase (warfarin-sensitive)

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

2-methyl-3-phytyl-1,4-naphthoquinone + oxidized dithiothreitol + H2O = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol

Reaction(s) (KEGG)

R03645 [Fig]Vitamin K <=>(2,3-epoxyphytyl)menaquinone
R03511 [Fig]2-Methyl-3-phytyl-1,4-naphthoquinone + Oxidized dithiothreitol + H2O <=>(2,3-epoxyphytyl)menaquinone + 1,4-Dithiothreitol

Inhibitor(s)

Warfarin
BiSSCat v1.06.20 http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.