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Home Help FGROUP SUBSTRUCTURE compound enzyme Multiple

EC 1.1.1.34 hydroxymethylglutaryl-CoA reductase (NADPH)

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

(R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADPH + 2 H+

Reaction(s) (KEGG)

R02082 [Fig](R)-Mevalonate + CoA + 2 NADP+ <=>(S)-3-Hydroxy-3-methylglutaryl-CoA + 2 NADPH

Inhibitor(s)

Pravastatin
BiSSCat v1.06.20 http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.