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EC 4.4.1.1 cystathionine gamma-lyase

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

L-cystathionine + H2O = L-cysteine + NH3 + 2-oxobutanoate

Reaction(s) (KEGG)

R01001 [Fig]L-Cystathionine + H2O <=>L-Cysteine + Ammonia + 2-Ketobutyric acid
R04930 [Fig]Selenocystathionine + H2O <=>Selenocysteine + Ammonia + 2-Ketobutyric acid
R00782 [Fig]L-Cysteine + H2O <=>H2S + 2-Oxopropanoate + Ammonia
R02408 [Fig]L-Cystine + H2O <=>2-Oxopropanoate + Ammonia + Thiocysteine

Cofactor(s)

Pyridoxal 5'-phosphate

Effector(s)

2-Amino-3-mercaptopropionic acid
BiSSCat v1.06.20 http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.