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EC 2.5.1.21 farnesyl-diphosphate farnesyltransferase

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

(1) 2 farnesyl diphosphate = diphosphate + presqualene diphosphate; (2) presqualene diphosphate + NAD(P)H + H+ = squalene + diphosphate + NAD(P)+

Reaction(s) (KEGG)

R00702 [Fig]2 2-trans,6-trans-Farnesyl diphosphate <=>Diphosphate + Presqualene diphosphate + H+
R06223 [Fig]2 2-trans,6-trans-Farnesyl diphosphate + NADPH + H+ <=>Spinacene + 2 Diphosphate + NADP+
R02872 [Fig]Presqualene diphosphate + NADPH + H+ <=>Diphosphate + Spinacene + NADP+

Inhibitor(s)

alpha-Phosphono sulfonate triacid
BiSSCat v1.06.20 http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.