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EC 1.14.99.3 heme oxygenase (decyclizing)

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

heme + 3 AH2 + 3 O2 = biliverdin + Fe2+ + CO + 3 A + 3 H2O

Reaction(s) (KEGG)

R00311 [Fig]Haem + 3 Reduced acceptor + 3 O2 <=>Biliverdin + CO + C14818 + 3 Acceptor + 3 H2O
R03683 [Fig]Hemoglobin + FADH2 + 3 O2 <=>Globin + Biliverdin + CO + C14819 + FAD + 3 H2O

Cofactor(s)

NADH
NADPH

Inhibitor(s)

Zinc protoporphyrin
BiSSCat v1.06.20 http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.