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EC 1.14.13.72 methylsterol monooxygenase

IUBMB ExplorEnz BRENDA KEGG ExPASy ERGO

Equation(s) (IUBMB)

(1) 4,4-dimethyl-5alpha-cholest-7-en-3beta-ol + NAD(P)H + H+ + O2 = 4beta-hydroxymethyl-4alpha-methyl-5alpha-cholest-7-en-3beta-ol + NAD(P)+ + H2O; (2) 4beta-hydroxymethyl-4alpha-methyl-5alpha-cholest-7-en-3beta-ol + NAD(P)H + H+ + O2 = 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + NAD(P)+ + 2 H2O; (3) 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + NAD(P)H + H+ + O2 = 3beta-hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + NAD(P)+ + H2O

Reaction(s) (KEGG)

R04328 [Fig]5alpha-Cholest-8-en-3beta-ol + CO2 + 4 H2O + 3 NADP+ <=>4alpha-Methyl-5alpha-cholesta-7-en-3beta-ol + 3 O2 + 3 NADPH + 3 H+
R04501 [Fig]4,4-Dimethyl-5alpha-cholest-7-en-3beta-ol + NADH + H+ + O2 <=>4beta-Hydroxymethyl-4alpha-methyl-5alpha-cholest-7-en-3beta-ol + NAD+ + H2O
R05733 [Fig]4beta-Hydroxymethyl-4alpha-methyl-5alpha-cholest-7-en-3beta-ol + NADH + H+ + O2 <=>3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + NAD+ + 2 H2O
R05734 [Fig]3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + NAD+ + H+ + O2 <=>3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + NADH + H2O
R05736 [Fig]4,4-Dimethyl-5alpha-cholest-7-en-3beta-ol + NADPH + H+ + O2 <=>4beta-Hydroxymethyl-4alpha-methyl-5alpha-cholest-7-en-3beta-ol + NADP+ + H2O
R05737 [Fig]4beta-Hydroxymethyl-4alpha-methyl-5alpha-cholest-7-en-3beta-ol + NADPH + H+ + O2 <=>3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + NADP+ + 2 H2O
R05738 [Fig]3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carbaldehyde + NADPH + H+ + O2 <=>3beta-Hydroxy-4beta-methyl-5alpha-cholest-7-ene-4alpha-carboxylate + NADP+ + H2O
R04669 [Fig]14-Demethyllanosterol + 6 O2 + 6 NADPH + 6 H+ <=>5alpha-Cholesta-8,24-dien-3beta-ol + 2 CO2 + 8 H2O + 6 NADP+

BiSSCat v1.06.20 http://bisscat.org/
Developed by Masaaki Kotera, Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.