GREP C14109

Selected compound(s)

C14109 2-Hydroxy-4-hydroxymethylbenzoic acid

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.2.1.- : 2-Hydroxy-4-hydroxymethyl-benzaldehyde + H2O + NAD+ = 2-Hydroxy-4-hydroxymethylbenzoic acid + NADH + H+
[Fig] 1.2.1.- : 2-Hydroxy-4-hydroxymethyl-benzaldehyde + H2O + NADP+ = 2-Hydroxy-4-hydroxymethylbenzoic acid + NADPH + H+
[Fig] 1.2.3.- : 2-Hydroxy-4-hydroxymethyl-benzaldehyde + H2O + O2 = 2-Hydroxy-4-hydroxymethylbenzoic acid + H2O2
[Fig] 1.14.11.- : 2-Hydroxy-4-methylbenzoic acid + O2 + 2-Ketoglutaric acid = 2-Hydroxy-4-hydroxymethylbenzoic acid + CO2 + Butanedionic acid
[Fig] 1.14.13.- : 2-Hydroxy-4-hydroxymethylbenzoic acid + H2O + NAD+ = 2-Hydroxy-4-methylbenzoic acid + NADH + O2 + H+
[Fig] 1.14.13.- : 2-Hydroxy-4-hydroxymethylbenzoic acid + H2O + NADP+ = 2-Hydroxy-4-methylbenzoic acid + NADPH + O2 + H+
[Fig] 1.14.16.- : 2-Hydroxy-4-hydroxymethylbenzoic acid + 6,7-Dihydrobiopterin + H2O = 2-Hydroxy-4-methylbenzoic acid + 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + O2
[Fig] 1.14.17.- : 2-Hydroxy-4-methylbenzoic acid + Vitamin C + O2 = 2-Hydroxy-4-hydroxymethylbenzoic acid + Dehydroascorbate + H2O

Reported reactions

[Fig] EC 1.2.1.- : 2-Hydroxy-4-hydroxymethyl-benzaldehyde + NAD+ + H2O = 2-Hydroxy-4-hydroxymethylbenzoic acid + NADH + H+
[Fig] EC 1.14.13.1 : 2-Hydroxy-4-hydroxymethylbenzoic acid + O2 + NADH + H+ = 4-Hydroxymethylcatechol + NAD+ + H2O + CO2

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.