GREP C06603

Selected compound(s)

C06603 4-Hydroxymuconic semialdehyde

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.2.1.- : 4-Hydroxymuconic semialdehyde + H2O + NADP+ = 2-Maleylacetate + NADPH + H+
[Fig] 1.2.3.- : 4-Hydroxymuconic semialdehyde + H2O + O2 = 2-Maleylacetate + H2O2
[Fig] 1.2.4.- : 4-Hydroxymuconic semialdehyde + H2O + Oxidized thioredoxin = 2-Maleylacetate + Reduced thioredoxin
[Fig] 1.2.4.- : 4-Hydroxymuconic semialdehyde + H2O + Oxidized dithiothreitol = 2-Maleylacetate + 1,4-Dithiothreitol
[Fig] 1.14.11.- : 4-Hydroxymuconic semialdehyde + O2 + 2-Ketoglutaric acid = 2-Maleylacetate + CO2 + Butanedionic acid
[Fig] 1.14.13.- : 2-Maleylacetate + H2O + NAD+ = 4-Hydroxymuconic semialdehyde + NADH + O2 + H+
[Fig] 1.14.13.- : 2-Maleylacetate + H2O + NADP+ = 4-Hydroxymuconic semialdehyde + NADPH + O2 + H+
[Fig] 1.14.16.- : 2-Maleylacetate + 6,7-Dihydrobiopterin + H2O = 4-Hydroxymuconic semialdehyde + 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + O2
[Fig] 1.14.17.- : 4-Hydroxymuconic semialdehyde + Vitamin C + O2 = 2-Maleylacetate + Dehydroascorbate + H2O

Reported reactions

[Fig] EC 1.13.11.- : 1,4-Benzenediol + O2 = 4-Hydroxymuconic semialdehyde
[Fig] EC 1.2.1.61 : 4-Hydroxymuconic semialdehyde + NAD+ + H2O = 2-Maleylacetate + NADH + H+

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.