GREP C06001

Selected compound(s)

C06001 (S)-3-Hydroxyisobutyrate

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.1.1.- : (S)-3-Hydroxyisobutyrate + NAD+ = (S)-Methylmalonate semialdehyde + NADH + H+
[Fig] 1.1.1.- : (S)-Methylmalonate semialdehyde + NADPH + H+ = (S)-3-Hydroxyisobutyrate + NADP+
[Fig] 1.1.3.- : (S)-3-Hydroxyisobutyrate + O2 = (S)-Methylmalonate semialdehyde + H2O2
[Fig] 1.1.4.- : (S)-Methylmalonate semialdehyde + 1,4-Dithiothreitol = (S)-3-Hydroxyisobutyrate + Oxidized dithiothreitol
[Fig] 1.1.5.- : (S)-Methylmalonate semialdehyde + CoQH2 = (S)-3-Hydroxyisobutyrate + CoQ
[Fig] 1.1.99.- : (S)-3-Hydroxyisobutyrate + FAD = (S)-Methylmalonate semialdehyde + FADH2
[Fig] 1.1.99.- : (S)-3-Hydroxyisobutyrate + Coenzyme F420 = (S)-Methylmalonate semialdehyde + Reduced coenzyme F420
[Fig] 3.1.2.- : (S)-3-Hydroxyisobutyryl-CoA + H2O = CoA + (S)-3-Hydroxyisobutyrate
[Fig] 3.5.99.- : 3-Aminoisobutanoate + H2O = (S)-3-Hydroxyisobutyrate + Ammonia
[Fig] 6.2.1.- : CoA + (S)-3-Hydroxyisobutyrate + ATP = (S)-3-Hydroxyisobutyryl-CoA + ADP + Orthophosphate
[Fig] 6.2.1.- : CoA + (S)-3-Hydroxyisobutyrate + ATP = (S)-3-Hydroxyisobutyryl-CoA + Diphosphate + 5'-AMP
[Fig] 6.3.4.- : (S)-3-Hydroxyisobutyrate + ATP + Ammonia = 3-Aminoisobutanoate + ADP + Orthophosphate
[Fig] 6.3.4.- : (S)-3-Hydroxyisobutyrate + ATP + Ammonia = 3-Aminoisobutanoate + Diphosphate + 5'-AMP

Reported reactions

[Fig] EC 3.1.2.4 : (S)-3-Hydroxyisobutyryl-CoA + H2O = CoA + (S)-3-Hydroxyisobutyrate
[Fig] EC 1.1.1.31 : (S)-3-Hydroxyisobutyrate + NAD+ = (S)-Methylmalonate semialdehyde + NADH + H+
[Fig] EC 1.1.1.35 : (S)-3-Hydroxyisobutyrate + NAD+ = (S)-Methylmalonate semialdehyde + NADH + H+

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.