GREP C05469

Selected compound(s)

C05469 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.1.1.- : 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + NADPH + H+ = Urocortisone + NADP+
[Fig] 1.1.1.- : Urocortisone + NAD+ = 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + NADH + H+
[Fig] 1.1.3.- : Urocortisone + O2 = 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + H2O2
[Fig] 1.1.4.- : 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + 1,4-Dithiothreitol = Urocortisone + Oxidized dithiothreitol
[Fig] 1.1.5.- : 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + Reduced thioredoxin = Urocortisone + Oxidized thioredoxin
[Fig] 1.1.5.- : 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + CoQH2 = Urocortisone + CoQ
[Fig] 1.1.5.- : Urocortisone + Coenzyme F420 = 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + Reduced coenzyme F420
[Fig] 1.1.99.- : Urocortisone + FAD = 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + FADH2
[Fig] 1.3.1.- : 17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione + NADPH + H+ = 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + NADP+
[Fig] 1.3.1.- : 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + NAD+ = 17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione + NADH + H+
[Fig] 1.3.3.- : 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + O2 = 17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione + H2O2
[Fig] 1.3.4.- : 17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione + 1,4-Dithiothreitol = 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + Oxidized dithiothreitol
[Fig] 1.3.5.- : 17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione + CoQH2 = 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + CoQ
[Fig] 1.3.99.- : 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + FAD = 17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione + FADH2
[Fig] 1.3.99.- : 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + Coenzyme F420 = 17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione + Reduced coenzyme F420

Reported reactions

[Fig] EC 1.1.1.50 : 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + H+ + NADPH = Urocortisone + NADP+
[Fig] EC 1.3.1.3 : 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + NADP+ = 17alpha,21-Dihydroxy-4-pregnene-3,11,20-trione + NADPH + H+
[Fig] EC 1.1.1.50 : Urocortisone + NAD+ = 17alpha,21-Dihydroxy-5beta-pregnane-3,11,20-trione + NADH + H+

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.