GREP C05452

Selected compound(s)

C05452 3alpha,7alpha-Dihydroxy-5beta-cholestane

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.1.1.- : 7alpha-Hydroxy-5beta-cholestan-3-one + NADPH + H+ = 3alpha,7alpha-Dihydroxy-5beta-cholestane + NADP+
[Fig] 1.1.1.- : 3alpha,7alpha-Dihydroxy-5beta-cholestane + NAD+ = 7alpha-Hydroxy-5beta-cholestan-3-one + NADH + H+
[Fig] 1.1.3.- : 3alpha,7alpha-Dihydroxy-5beta-cholestane + O2 = 7alpha-Hydroxy-5beta-cholestan-3-one + H2O2
[Fig] 1.1.4.- : 7alpha-Hydroxy-5beta-cholestan-3-one + 1,4-Dithiothreitol = 3alpha,7alpha-Dihydroxy-5beta-cholestane + Oxidized dithiothreitol
[Fig] 1.1.5.- : 7alpha-Hydroxy-5beta-cholestan-3-one + Reduced thioredoxin = 3alpha,7alpha-Dihydroxy-5beta-cholestane + Oxidized thioredoxin
[Fig] 1.1.5.- : 7alpha-Hydroxy-5beta-cholestan-3-one + CoQH2 = 3alpha,7alpha-Dihydroxy-5beta-cholestane + CoQ
[Fig] 1.1.5.- : 3alpha,7alpha-Dihydroxy-5beta-cholestane + Coenzyme F420 = 7alpha-Hydroxy-5beta-cholestan-3-one + Reduced coenzyme F420
[Fig] 1.1.99.- : 3alpha,7alpha-Dihydroxy-5beta-cholestane + FAD = 7alpha-Hydroxy-5beta-cholestan-3-one + FADH2
[Fig] 1.14.11.- : 3alpha,7alpha-Dihydroxy-5beta-cholestane + O2 + 2-Ketoglutaric acid = 3alpha,7alpha,26-Trihydroxy-5beta-cholestane + CO2 + Butanedionic acid
[Fig] 1.14.13.- : 3alpha,7alpha,26-Trihydroxy-5beta-cholestane + H2O + NAD+ = 3alpha,7alpha-Dihydroxy-5beta-cholestane + NADH + O2 + H+
[Fig] 1.14.13.- : 3alpha,7alpha,26-Trihydroxy-5beta-cholestane + H2O + NADP+ = 3alpha,7alpha-Dihydroxy-5beta-cholestane + NADPH + O2 + H+
[Fig] 1.14.16.- : 3alpha,7alpha,26-Trihydroxy-5beta-cholestane + 6,7-Dihydrobiopterin + H2O = 3alpha,7alpha-Dihydroxy-5beta-cholestane + 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + O2
[Fig] 1.14.17.- : 3alpha,7alpha-Dihydroxy-5beta-cholestane + Vitamin C + O2 = 3alpha,7alpha,26-Trihydroxy-5beta-cholestane + Dehydroascorbate + H2O

Reported reactions

[Fig] EC 1.1.1.50 : 3alpha,7alpha-Dihydroxy-5beta-cholestane + NAD+ = 7alpha-Hydroxy-5beta-cholestan-3-one + NADH + H+
[Fig] EC 1.1.1.53 : 3alpha,7alpha-Dihydroxy-5beta-cholestane + NAD+ = 7alpha-Hydroxy-5beta-cholestan-3-one + NADH + H+
[Fig] EC 1.1.1.50 : 3alpha,7alpha-Dihydroxy-5beta-cholestane + NADP+ = 7alpha-Hydroxy-5beta-cholestan-3-one + NADPH + H+
[Fig] EC 1.1.1.53 : 3alpha,7alpha-Dihydroxy-5beta-cholestane + NADP+ = 7alpha-Hydroxy-5beta-cholestan-3-one + NADPH + H+
[Fig] EC 1.14.13.15 : 3alpha,7alpha-Dihydroxy-5beta-cholestane + NADPH + O2 + H+ = 3alpha,7alpha,26-Trihydroxy-5beta-cholestane + NADP+ + H2O

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.