GREP C05451

Selected compound(s)

C05451 7alpha-Hydroxy-5beta-cholestan-3-one

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.1.1.- : 7alpha-Hydroxy-5beta-cholestan-3-one + NADPH + H+ = 3alpha,7alpha-Dihydroxy-5beta-cholestane + NADP+
[Fig] 1.1.1.- : 3alpha,7alpha-Dihydroxy-5beta-cholestane + NAD+ = 7alpha-Hydroxy-5beta-cholestan-3-one + NADH + H+
[Fig] 1.1.3.- : 3alpha,7alpha-Dihydroxy-5beta-cholestane + O2 = 7alpha-Hydroxy-5beta-cholestan-3-one + H2O2
[Fig] 1.1.4.- : 7alpha-Hydroxy-5beta-cholestan-3-one + 1,4-Dithiothreitol = 3alpha,7alpha-Dihydroxy-5beta-cholestane + Oxidized dithiothreitol
[Fig] 1.1.5.- : 7alpha-Hydroxy-5beta-cholestan-3-one + Reduced thioredoxin = 3alpha,7alpha-Dihydroxy-5beta-cholestane + Oxidized thioredoxin
[Fig] 1.1.5.- : 7alpha-Hydroxy-5beta-cholestan-3-one + CoQH2 = 3alpha,7alpha-Dihydroxy-5beta-cholestane + CoQ
[Fig] 1.1.5.- : 3alpha,7alpha-Dihydroxy-5beta-cholestane + Coenzyme F420 = 7alpha-Hydroxy-5beta-cholestan-3-one + Reduced coenzyme F420
[Fig] 1.1.99.- : 3alpha,7alpha-Dihydroxy-5beta-cholestane + FAD = 7alpha-Hydroxy-5beta-cholestan-3-one + FADH2
[Fig] 1.3.1.- : 7alpha-Hydroxy-5beta-cholestan-3-one + NAD+ = 7alpha-Hydroxycholest-4-en-3-one + NADH + H+
[Fig] 1.3.1.- : 7alpha-Hydroxycholest-4-en-3-one + NADPH + H+ = 7alpha-Hydroxy-5beta-cholestan-3-one + NADP+
[Fig] 1.3.3.- : 7alpha-Hydroxy-5beta-cholestan-3-one + O2 = 7alpha-Hydroxycholest-4-en-3-one + H2O2
[Fig] 1.3.4.- : 7alpha-Hydroxycholest-4-en-3-one + 1,4-Dithiothreitol = 7alpha-Hydroxy-5beta-cholestan-3-one + Oxidized dithiothreitol
[Fig] 1.3.5.- : 7alpha-Hydroxycholest-4-en-3-one + CoQH2 = 7alpha-Hydroxy-5beta-cholestan-3-one + CoQ
[Fig] 1.3.99.- : 7alpha-Hydroxy-5beta-cholestan-3-one + FAD = 7alpha-Hydroxycholest-4-en-3-one + FADH2
[Fig] 1.3.99.- : 7alpha-Hydroxy-5beta-cholestan-3-one + Coenzyme F420 = 7alpha-Hydroxycholest-4-en-3-one + Reduced coenzyme F420

Reported reactions

[Fig] EC 1.3.99.6 : 7alpha-Hydroxy-5beta-cholestan-3-one + NADP+ = 7alpha-Hydroxycholest-4-en-3-one + NADPH + H+
[Fig] EC 1.1.1.50 : 3alpha,7alpha-Dihydroxy-5beta-cholestane + NAD+ = 7alpha-Hydroxy-5beta-cholestan-3-one + NADH + H+
[Fig] EC 1.1.1.53 : 3alpha,7alpha-Dihydroxy-5beta-cholestane + NAD+ = 7alpha-Hydroxy-5beta-cholestan-3-one + NADH + H+
[Fig] EC 1.1.1.50 : 3alpha,7alpha-Dihydroxy-5beta-cholestane + NADP+ = 7alpha-Hydroxy-5beta-cholestan-3-one + NADPH + H+
[Fig] EC 1.1.1.53 : 3alpha,7alpha-Dihydroxy-5beta-cholestane + NADP+ = 7alpha-Hydroxy-5beta-cholestan-3-one + NADPH + H+

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.