Selected compound(s)
Each orphan metabolite is emphasized in bold.
Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions |
Reported reactions]
Suggested reactions
- [Fig] 1.3.1.- : 14-Demethyllanosterol + NAD+ = 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADH + H+
- [Fig] 1.3.1.- : 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H+ = 14-Demethyllanosterol + NADP+
- [Fig] 1.3.3.- : 14-Demethyllanosterol + O2 = 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + H2O2
- [Fig] 1.3.4.- : 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + 1,4-Dithiothreitol = 14-Demethyllanosterol + Oxidized dithiothreitol
- [Fig] 1.3.5.- : 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + CoQH2 = 14-Demethyllanosterol + CoQ
- [Fig] 1.3.99.- : 14-Demethyllanosterol + FAD = 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + FADH2
- [Fig] 1.3.99.- : 14-Demethyllanosterol + Coenzyme F420 = 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + Reduced coenzyme F420
- [Fig] 2.1.1.- : 14-Demethyllanosterol + S-Adenosyl-L-methionine = 4,4',14alpha-Trimethyl-5alpha-cholesta-8,24-dien-3beta-ol + S-Adenosyl-L-homocysteine
- [Fig] 2.1.1.- : 14-Demethyllanosterol + S-Adenosyl-L-methionine = 4,4',14alpha-Trimethyl-5alpha-cholesta-8,24-dien-3beta-ol + S-Adenosyl-L-homocysteine + H+
- [Fig] 3.3.2.- : 4,4',14alpha-Trimethyl-5alpha-cholesta-8,24-dien-3beta-ol + H2O = 14-Demethyllanosterol + Methanol
Reported reactions
- [Fig] EC 1.3.1.70 : 4,4',14alpha-Trimethyl-5alpha-cholesta-8,24-dien-3beta-ol + O2 + NADPH + H+ = 14-Demethyllanosterol + Formate + NADP+
- [Fig] EC 1.14.13.70 : 4,4',14alpha-Trimethyl-5alpha-cholesta-8,24-dien-3beta-ol + O2 + NADPH + H+ = 14-Demethyllanosterol + Formate + NADP+
- [Fig] EC 1.1.1.170 : 14-Demethyllanosterol + 6 O2 + 6 NADPH + 6 H+ = 5alpha-Cholesta-8,24-dien-3beta-ol + 2 CO2 + 8 H2O + 6 NADP+
- [Fig] EC 1.1.1.270 : 14-Demethyllanosterol + 6 O2 + 6 NADPH + 6 H+ = 5alpha-Cholesta-8,24-dien-3beta-ol + 2 CO2 + 8 H2O + 6 NADP+
- [Fig] EC 1.14.13.72 : 14-Demethyllanosterol + 6 O2 + 6 NADPH + 6 H+ = 5alpha-Cholesta-8,24-dien-3beta-ol + 2 CO2 + 8 H2O + 6 NADP+
- [Fig] EC 1.3.1.70 : 14-Demethyllanosterol + NADP+ = 4,4-Dimethyl-5alpha-cholesta-8,14,24-trien-3beta-ol + NADPH + H+
GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.