GREP C04751

Selected compound(s)

C04751 1-(5'-Phosphoribosyl)-4-carboxy-5-aminoimidazole

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 2.1.2.- : 1-(5'-Phosphoribosyl)-4-carboxy-5-aminoimidazole + THF = 1-(5'-Phosphoribosyl)-5-aminoimidazole + 10-Formyl-THF
[Fig] 2.3.1.- : 1-(5'-Phosphoribosyl)-4-carboxy-5-aminoimidazole + 1-beta-Aspartyl-N-acetyl-D-glucosaminylamine = (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido]succinate + N-Acetyl-beta-D-glucosaminylamine
[Fig] 3.5.1.- : (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido]succinate + H2O = 1-(5'-Phosphoribosyl)-4-carboxy-5-aminoimidazole + 2-Aminosuccinic acid
[Fig] 3.7.1.- : 1-(5'-Phosphoribosyl)-4-carboxy-5-aminoimidazole + H2O = 1-(5'-Phosphoribosyl)-5-aminoimidazole + Formate
[Fig] 4.1.1.- : 1-(5'-Phosphoribosyl)-5-aminoimidazole + CO2 = 1-(5'-Phosphoribosyl)-4-carboxy-5-aminoimidazole
[Fig] 6.3.1.- : 1-(5'-Phosphoribosyl)-4-carboxy-5-aminoimidazole + 2-Aminosuccinic acid + ATP = (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido]succinate + ADP + Orthophosphate
[Fig] 6.3.1.- : 1-(5'-Phosphoribosyl)-4-carboxy-5-aminoimidazole + 2-Aminosuccinic acid + ATP = (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido]succinate + Diphosphate + 5'-AMP
[Fig] 6.4.1.- : 1-(5'-Phosphoribosyl)-5-aminoimidazole + ATP + Acid carbonate = 1-(5'-Phosphoribosyl)-4-carboxy-5-aminoimidazole + ADP + Orthophosphate
[Fig] 6.4.1.- : 1-(5'-Phosphoribosyl)-4-carboxy-5-aminoimidazole + ADP + Orthophosphate = 1-(5'-Phosphoribosyl)-5-aminoimidazole + Formate + ATP

Reported reactions

[Fig] EC 6.3.2.6 : ATP + 1-(5'-Phosphoribosyl)-4-carboxy-5-aminoimidazole + 2-Aminosuccinic acid = ADP + Orthophosphate + (S)-2-[5-Amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido]succinate
[Fig] EC 4.1.1.21 : 1-(5'-Phosphoribosyl)-4-carboxy-5-aminoimidazole = 1-(5'-Phosphoribosyl)-5-aminoimidazole + CO2

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.