GREP C04483

Selected compound(s)

C04483 3alpha,12alpha-Dihydroxy-5beta-cholanate

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.3.1.- : 3alpha,12alpha-Dihydroxy-5beta-cholanate + NAD+ = 3alpha,12alpha-Dihydroxy-5beta-chol-6-enoate + NADH + H+
[Fig] 1.3.1.- : 3alpha,12alpha-Dihydroxy-5beta-chol-6-enoate + NADPH + H+ = 3alpha,12alpha-Dihydroxy-5beta-cholanate + NADP+
[Fig] 1.3.3.- : 3alpha,12alpha-Dihydroxy-5beta-cholanate + O2 = 3alpha,12alpha-Dihydroxy-5beta-chol-6-enoate + H2O2
[Fig] 1.3.4.- : 3alpha,12alpha-Dihydroxy-5beta-chol-6-enoate + 1,4-Dithiothreitol = 3alpha,12alpha-Dihydroxy-5beta-cholanate + Oxidized dithiothreitol
[Fig] 1.3.5.- : 3alpha,12alpha-Dihydroxy-5beta-chol-6-enoate + CoQH2 = 3alpha,12alpha-Dihydroxy-5beta-cholanate + CoQ
[Fig] 1.3.99.- : 3alpha,12alpha-Dihydroxy-5beta-cholanate + FAD = 3alpha,12alpha-Dihydroxy-5beta-chol-6-enoate + FADH2
[Fig] 1.3.99.- : 3alpha,12alpha-Dihydroxy-5beta-cholanate + Coenzyme F420 = 3alpha,12alpha-Dihydroxy-5beta-chol-6-enoate + Reduced coenzyme F420
[Fig] 1.14.11.- : 3alpha,12alpha-Dihydroxy-5beta-cholanate + O2 + 2-Ketoglutaric acid = 3alpha,7alpha,12alpha-Trihydroxy-5beta-cholanate + CO2 + Butanedionic acid
[Fig] 1.14.11.- : 3alpha,12alpha-Dihydroxy-5beta-cholanate + O2 + 2-Ketoglutaric acid = Bile acid + CO2 + Butanedionic acid
[Fig] 3.5.1.- : Taurodeoxycholate + H2O = 2-Aminoethanesulfonic acid + 3alpha,12alpha-Dihydroxy-5beta-cholanate
[Fig] 3.5.1.- : Glycodeoxycholate + H2O = Glycine + 3alpha,12alpha-Dihydroxy-5beta-cholanate
[Fig] 6.3.1.- : Glycine + 3alpha,12alpha-Dihydroxy-5beta-cholanate + ATP = Glycodeoxycholate + ADP + Orthophosphate
[Fig] 6.3.1.- : Glycine + 3alpha,12alpha-Dihydroxy-5beta-cholanate + ATP = Glycodeoxycholate + Diphosphate + 5'-AMP
[Fig] 6.3.1.- : 2-Aminoethanesulfonic acid + 3alpha,12alpha-Dihydroxy-5beta-cholanate + ATP = Taurodeoxycholate + ADP + Orthophosphate
[Fig] 6.3.1.- : 2-Aminoethanesulfonic acid + 3alpha,12alpha-Dihydroxy-5beta-cholanate + ATP = Taurodeoxycholate + Diphosphate + 5'-AMP

Reported reactions

[Fig] EC 3.5.1.24 : Glycodeoxycholate + H2O = 3alpha,12alpha-Dihydroxy-5beta-cholanate + Glycine
[Fig] EC 3.5.1.24 : Taurodeoxycholate + H2O = 3alpha,12alpha-Dihydroxy-5beta-cholanate + 2-Aminoethanesulfonic acid

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.