GREP C04244

Selected compound(s)

C04244 6-Lactoyl-5,6,7,8-tetrahydropterin

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.1.1.- : 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + NAD+ = 6-Lactoyl-5,6,7,8-tetrahydropterin + NADH + H+
[Fig] 1.1.1.- : 6-(1,2-Dioxopropyl)-5,6,7,8-tetrahydropterin + NADPH + H+ = 6-Lactoyl-5,6,7,8-tetrahydropterin + NADP+
[Fig] 1.1.1.- : 6-Lactoyl-5,6,7,8-tetrahydropterin + NAD+ = 6-(1,2-Dioxopropyl)-5,6,7,8-tetrahydropterin + NADH + H+
[Fig] 1.1.1.- : 6-Lactoyl-5,6,7,8-tetrahydropterin + NADPH + H+ = 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + NADP+
[Fig] 1.1.3.- : 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + O2 = 6-Lactoyl-5,6,7,8-tetrahydropterin + H2O2
[Fig] 1.1.3.- : 6-Lactoyl-5,6,7,8-tetrahydropterin + O2 = 6-(1,2-Dioxopropyl)-5,6,7,8-tetrahydropterin + H2O2
[Fig] 1.1.4.- : 6-(1,2-Dioxopropyl)-5,6,7,8-tetrahydropterin + 1,4-Dithiothreitol = 6-Lactoyl-5,6,7,8-tetrahydropterin + Oxidized dithiothreitol
[Fig] 1.1.4.- : 6-Lactoyl-5,6,7,8-tetrahydropterin + 1,4-Dithiothreitol = 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + Oxidized dithiothreitol
[Fig] 1.1.5.- : 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + Coenzyme F420 = 6-Lactoyl-5,6,7,8-tetrahydropterin + Reduced coenzyme F420
[Fig] 1.1.5.- : 6-(1,2-Dioxopropyl)-5,6,7,8-tetrahydropterin + Reduced thioredoxin = 6-Lactoyl-5,6,7,8-tetrahydropterin + Oxidized thioredoxin
[Fig] 1.1.5.- : 6-(1,2-Dioxopropyl)-5,6,7,8-tetrahydropterin + CoQH2 = 6-Lactoyl-5,6,7,8-tetrahydropterin + CoQ
[Fig] 1.1.5.- : 6-Lactoyl-5,6,7,8-tetrahydropterin + Reduced thioredoxin = 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + Oxidized thioredoxin
[Fig] 1.1.5.- : 6-Lactoyl-5,6,7,8-tetrahydropterin + CoQH2 = 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + CoQ
[Fig] 1.1.5.- : 6-Lactoyl-5,6,7,8-tetrahydropterin + Coenzyme F420 = 6-(1,2-Dioxopropyl)-5,6,7,8-tetrahydropterin + Reduced coenzyme F420
[Fig] 1.1.99.- : 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + FAD = 6-Lactoyl-5,6,7,8-tetrahydropterin + FADH2
[Fig] 1.1.99.- : 6-Lactoyl-5,6,7,8-tetrahydropterin + FAD = 6-(1,2-Dioxopropyl)-5,6,7,8-tetrahydropterin + FADH2

Reported reactions

[Fig] EC 1.1.1.153 : 6-Lactoyl-5,6,7,8-tetrahydropterin + NADP+ = 6-(1,2-Dioxopropyl)-5,6,7,8-tetrahydropterin + NADPH + H+
[Fig] EC 1.1.1.220 : 6-Lactoyl-5,6,7,8-tetrahydropterin + NADP+ = 6-(1,2-Dioxopropyl)-5,6,7,8-tetrahydropterin + NADPH + H+
[Fig] EC 1.1.1.153 : 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + NADP+ = 6-Lactoyl-5,6,7,8-tetrahydropterin + NADPH

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.