GREP C04042

Selected compound(s)

C04042 20alpha-Hydroxy-4-pregnen-3-one

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.1.1.- : 4-Pregnene-3,20-dione + NADPH + H+ = 20alpha-Hydroxy-4-pregnen-3-one + NADP+
[Fig] 1.1.1.- : 20alpha-Hydroxy-4-pregnen-3-one + NAD+ = 4-Pregnene-3,20-dione + NADH + H+
[Fig] 1.1.3.- : 20alpha-Hydroxy-4-pregnen-3-one + O2 = 4-Pregnene-3,20-dione + H2O2
[Fig] 1.1.4.- : 4-Pregnene-3,20-dione + 1,4-Dithiothreitol = 20alpha-Hydroxy-4-pregnen-3-one + Oxidized dithiothreitol
[Fig] 1.1.5.- : 4-Pregnene-3,20-dione + Reduced thioredoxin = 20alpha-Hydroxy-4-pregnen-3-one + Oxidized thioredoxin
[Fig] 1.1.5.- : 4-Pregnene-3,20-dione + CoQH2 = 20alpha-Hydroxy-4-pregnen-3-one + CoQ
[Fig] 1.1.5.- : 20alpha-Hydroxy-4-pregnen-3-one + Coenzyme F420 = 4-Pregnene-3,20-dione + Reduced coenzyme F420
[Fig] 1.1.99.- : 20alpha-Hydroxy-4-pregnen-3-one + FAD = 4-Pregnene-3,20-dione + FADH2
[Fig] 1.13.12.- : 11beta-Hydroxyprogesterone + H2O = 20alpha-Hydroxy-4-pregnen-3-one + O2
[Fig] 1.14.13.- : 20alpha-Hydroxy-4-pregnen-3-one + H2O + NAD+ = 11beta-Hydroxyprogesterone + NADH + H+
[Fig] 1.14.13.- : 20alpha-Hydroxy-4-pregnen-3-one + H2O + NADP+ = 11beta-Hydroxyprogesterone + NADPH + H+

Reported reactions

[Fig] EC 1.1.1.149 : 20alpha-Hydroxy-4-pregnen-3-one + NAD+ = 4-Pregnene-3,20-dione + NADH
[Fig] EC 1.1.1.149 : 20alpha-Hydroxy-4-pregnen-3-one + NADP+ = 4-Pregnene-3,20-dione + NADPH

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.