GREP C03772

Selected compound(s)

C03772 5beta-Androstane-3,17-dione

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.1.1.- : 5beta-Androstane-3,17-dione + NADPH + H+ = 3alpha-Hydroxy-5beta-androstan-17-one + NADP+
[Fig] 1.1.1.- : 5beta-Androstane-3,17-dione + NADPH + H+ = 5beta-Dihydrotestosterone + NADP+
[Fig] 1.1.1.- : 3alpha-Hydroxy-5beta-androstan-17-one + NAD+ = 5beta-Androstane-3,17-dione + NADH + H+
[Fig] 1.1.1.- : 5beta-Dihydrotestosterone + NAD+ = 5beta-Androstane-3,17-dione + NADH + H+
[Fig] 1.1.3.- : 3alpha-Hydroxy-5beta-androstan-17-one + O2 = 5beta-Androstane-3,17-dione + H2O2
[Fig] 1.1.3.- : 5beta-Dihydrotestosterone + O2 = 5beta-Androstane-3,17-dione + H2O2
[Fig] 1.1.4.- : 5beta-Androstane-3,17-dione + 1,4-Dithiothreitol = 3alpha-Hydroxy-5beta-androstan-17-one + Oxidized dithiothreitol
[Fig] 1.1.4.- : 5beta-Androstane-3,17-dione + 1,4-Dithiothreitol = 5beta-Dihydrotestosterone + Oxidized dithiothreitol
[Fig] 1.1.5.- : 5beta-Androstane-3,17-dione + Reduced thioredoxin = 3alpha-Hydroxy-5beta-androstan-17-one + Oxidized thioredoxin
[Fig] 1.1.5.- : 5beta-Androstane-3,17-dione + Reduced thioredoxin = 5beta-Dihydrotestosterone + Oxidized thioredoxin
[Fig] 1.1.5.- : 5beta-Androstane-3,17-dione + CoQH2 = 3alpha-Hydroxy-5beta-androstan-17-one + CoQ
[Fig] 1.1.5.- : 5beta-Androstane-3,17-dione + CoQH2 = 5beta-Dihydrotestosterone + CoQ
[Fig] 1.1.5.- : 3alpha-Hydroxy-5beta-androstan-17-one + Coenzyme F420 = 5beta-Androstane-3,17-dione + Reduced coenzyme F420
[Fig] 1.1.5.- : 5beta-Dihydrotestosterone + Coenzyme F420 = 5beta-Androstane-3,17-dione + Reduced coenzyme F420
[Fig] 1.1.99.- : 3alpha-Hydroxy-5beta-androstan-17-one + FAD = 5beta-Androstane-3,17-dione + FADH2
[Fig] 1.1.99.- : 5beta-Dihydrotestosterone + FAD = 5beta-Androstane-3,17-dione + FADH2
[Fig] 1.3.1.- : 4-Androstene-3,17-dione + NADPH + H+ = 5beta-Androstane-3,17-dione + NADP+
[Fig] 1.3.1.- : 5beta-Androstane-3,17-dione + NAD+ = 4-Androstene-3,17-dione + NADH + H+
[Fig] 1.3.3.- : 5beta-Androstane-3,17-dione + O2 = 4-Androstene-3,17-dione + H2O2
[Fig] 1.3.4.- : 4-Androstene-3,17-dione + 1,4-Dithiothreitol = 5beta-Androstane-3,17-dione + Oxidized dithiothreitol
[Fig] 1.3.5.- : 4-Androstene-3,17-dione + CoQH2 = 5beta-Androstane-3,17-dione + CoQ
[Fig] 1.3.99.- : 5beta-Androstane-3,17-dione + FAD = 4-Androstene-3,17-dione + FADH2
[Fig] 1.3.99.- : 5beta-Androstane-3,17-dione + Coenzyme F420 = 4-Androstene-3,17-dione + Reduced coenzyme F420
[Fig] 1.13.12.- : 11beta-Hydroxyandrost-4-ene-3,17-dione + H2O = 5beta-Androstane-3,17-dione + O2
[Fig] 1.13.12.- : 7alpha-Hydroxyandrost-4-ene-3,17-dione + H2O = 5beta-Androstane-3,17-dione + O2
[Fig] 1.14.13.- : 5beta-Androstane-3,17-dione + H2O + NAD+ = 11beta-Hydroxyandrost-4-ene-3,17-dione + NADH + H+
[Fig] 1.14.13.- : 5beta-Androstane-3,17-dione + H2O + NAD+ = 7alpha-Hydroxyandrost-4-ene-3,17-dione + NADH + H+
[Fig] 1.14.13.- : 5beta-Androstane-3,17-dione + H2O + NADP+ = 11beta-Hydroxyandrost-4-ene-3,17-dione + NADPH + H+
[Fig] 1.14.13.- : 5beta-Androstane-3,17-dione + H2O + NADP+ = 7alpha-Hydroxyandrost-4-ene-3,17-dione + NADPH + H+

Reported reactions

[Fig] EC 1.1.1.50 : 3alpha-Hydroxy-5beta-androstan-17-one + NAD+ = 5beta-Androstane-3,17-dione + NADH
[Fig] EC 1.1.1.152 : 3alpha-Hydroxy-5beta-androstan-17-one + NAD+ = 5beta-Androstane-3,17-dione + NADH
[Fig] EC 1.1.1.50 : 3alpha-Hydroxy-5beta-androstan-17-one + NADP+ = 5beta-Androstane-3,17-dione + NADPH
[Fig] EC 1.3.99.6 : 5beta-Androstane-3,17-dione + Acceptor = 4-Androstene-3,17-dione + Reduced acceptor

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.