GREP C03465

Selected compound(s)

C03465 2-Oxo-3-methylvalerate

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.4.1.- : L-Isoleucine + H2O + NAD+ = 2-Oxo-3-methylvalerate + NADH + Ammonia
[Fig] 1.4.1.- : L-Isoleucine + H2O + NAD+ = 2-Oxo-3-methylvalerate + NADH + Ammonia + H+
[Fig] 1.4.1.- : L-Isoleucine + H2O + NAD+ = 2-Oxo-3-methylvalerate + NADH + H+ + Ammonia
[Fig] 1.4.1.- : L-Isoleucine + H2O + NADP+ = 2-Oxo-3-methylvalerate + NADPH + Ammonia
[Fig] 1.4.1.- : L-Isoleucine + H2O + NADP+ = 2-Oxo-3-methylvalerate + NADPH + Ammonia + H+
[Fig] 1.4.1.- : L-Isoleucine + H2O + NADP+ = 2-Oxo-3-methylvalerate + NADPH + H+ + Ammonia
[Fig] 1.4.1.- : L-Isoleucine + NAD+ + H2O = 2-Oxo-3-methylvalerate + Ammonia + NADH
[Fig] 1.4.1.- : L-Isoleucine + NAD+ + H2O = 2-Oxo-3-methylvalerate + Ammonia + NADH + H+
[Fig] 1.4.1.- : L-Isoleucine + NADP+ + H2O = 2-Oxo-3-methylvalerate + Ammonia + NADPH
[Fig] 1.4.1.- : L-Isoleucine + NADP+ + H2O = 2-Oxo-3-methylvalerate + Ammonia + NADPH + H+
[Fig] 1.4.3.- : L-Isoleucine + H2O + O2 = 2-Oxo-3-methylvalerate + Ammonia + H2O2
[Fig] 2.6.1.- : L-Isoleucine + Pyridoxal 5'-phosphate = 2-Oxo-3-methylvalerate + Pyridoxamine 5'-phosphate
[Fig] 2.6.1.- : 2-Oxo-3-methylvalerate + L-Glutamate = L-Isoleucine + 2-Ketoglutaric acid

Reported reactions

[Fig] EC 1.2.4.4 : 2-Oxo-3-methylvalerate + Lipoamide = S-(2-Methylbutanoyl)-dihydrolipoamide + CO2
[Fig] EC 1.2.1.25 : 2-Oxo-3-methylvalerate + CoA + NAD+ = 2-Methylbutanoyl-CoA + CO2 + NADH
[Fig] EC 1.4.3.2 : L-Isoleucine + O2 + H2O = 2-Oxo-3-methylvalerate + Ammonia + H2O2
[Fig] EC 2.6.1.42 : L-Isoleucine + 2-Ketoglutaric acid = 2-Oxo-3-methylvalerate + L-Glutamate

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.