GREP C03459

Selected compound(s)

C03459 2-Hydroxy-3-oxosuccinate

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.1.1.- : meso-Tartaric acid + NAD+ = 2-Hydroxy-3-oxosuccinate + NADH + H+
[Fig] 1.1.1.- : (+)-Tartaric acid + NAD+ = 2-Hydroxy-3-oxosuccinate + NADH + H+
[Fig] 1.1.1.- : 2-Hydroxy-3-oxosuccinate + NADPH + H+ = meso-Tartaric acid + NADP+
[Fig] 1.1.1.- : 2-Hydroxy-3-oxosuccinate + NADPH + H+ = (+)-Tartaric acid + NADP+
[Fig] 1.1.3.- : meso-Tartaric acid + O2 = 2-Hydroxy-3-oxosuccinate + H2O2
[Fig] 1.1.3.- : (+)-Tartaric acid + O2 = 2-Hydroxy-3-oxosuccinate + H2O2
[Fig] 1.1.4.- : 2-Hydroxy-3-oxosuccinate + 1,4-Dithiothreitol = meso-Tartaric acid + Oxidized dithiothreitol
[Fig] 1.1.4.- : 2-Hydroxy-3-oxosuccinate + 1,4-Dithiothreitol = (+)-Tartaric acid + Oxidized dithiothreitol
[Fig] 1.1.5.- : meso-Tartaric acid + Coenzyme F420 = 2-Hydroxy-3-oxosuccinate + Reduced coenzyme F420
[Fig] 1.1.5.- : (+)-Tartaric acid + Coenzyme F420 = 2-Hydroxy-3-oxosuccinate + Reduced coenzyme F420
[Fig] 1.1.5.- : 2-Hydroxy-3-oxosuccinate + Reduced thioredoxin = meso-Tartaric acid + Oxidized thioredoxin
[Fig] 1.1.5.- : 2-Hydroxy-3-oxosuccinate + Reduced thioredoxin = (+)-Tartaric acid + Oxidized thioredoxin
[Fig] 1.1.5.- : 2-Hydroxy-3-oxosuccinate + CoQH2 = meso-Tartaric acid + CoQ
[Fig] 1.1.5.- : 2-Hydroxy-3-oxosuccinate + CoQH2 = (+)-Tartaric acid + CoQ
[Fig] 1.1.99.- : meso-Tartaric acid + FAD = 2-Hydroxy-3-oxosuccinate + FADH2
[Fig] 1.1.99.- : (+)-Tartaric acid + FAD = 2-Hydroxy-3-oxosuccinate + FADH2
[Fig] 1.2.1.- : (R)-Glycerate + NAD+ + CO2 + H+ = 2-Hydroxy-3-oxosuccinate + NADH
[Fig] 1.2.1.- : (R)-Glycerate + NAD+ + CO2 = 2-Hydroxy-3-oxosuccinate + NADH
[Fig] 1.2.1.- : 2-Hydroxy-3-oxosuccinate + NADPH = (R)-Glycerate + NADP+ + CO2
[Fig] 1.2.1.- : 2-Hydroxy-3-oxosuccinate + NADPH = (R)-Glycerate + NADP+ + CO2 + H+
[Fig] 1.14.11.- : keto-Oxaloacetate + O2 + 2-Ketoglutaric acid = 2-Hydroxy-3-oxosuccinate + CO2 + Butanedionic acid

Reported reactions

[Fig] EC 1.1.1.92 : (R)-Glycerate + NADP+ + CO2 = 2-Hydroxy-3-oxosuccinate + NADPH
[Fig] EC 1.1.1.93 : meso-Tartaric acid + NAD+ = 2-Hydroxy-3-oxosuccinate + NADH
[Fig] EC 1.1.1.93 : (+)-Tartaric acid + NAD+ = 2-Hydroxy-3-oxosuccinate + NADH + H+
[Fig] EC 1.1.1.92 : (R)-Glycerate + NAD+ + CO2 = 2-Hydroxy-3-oxosuccinate + NADH

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.