GREP C02501

Selected compound(s)

C02501 2-Hydroxymuconate

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.2.1.- : 2-Hydroxymuconate semialdehyde + H2O + NAD+ = 2-Hydroxymuconate + NADH + H+
[Fig] 1.2.1.- : 2-Hydroxymuconate semialdehyde + H2O + NADP+ = 2-Hydroxymuconate + NADPH + H+
[Fig] 1.2.3.- : 2-Hydroxymuconate semialdehyde + H2O + O2 = 2-Hydroxymuconate + H2O2
[Fig] 2.1.1.- : 2-Hydroxymuconate + S-Adenosyl-L-methionine = 2-Hydroxy-5-methyl-cis,cis-muconate + S-Adenosyl-L-homocysteine
[Fig] 2.1.1.- : 2-Hydroxymuconate + S-Adenosyl-L-methionine = 2-Hydroxy-5-methyl-cis,cis-muconate + S-Adenosyl-L-homocysteine + H+
[Fig] 3.1.1.- : 2-Hydroxy-6-oxo-6-(2-hydroxyphenoxy)-hexa-2,4-dienoate + H2O = 1,2-Benzenediol + 2-Hydroxymuconate
[Fig] 3.3.2.- : 2-Hydroxy-5-methyl-cis,cis-muconate + H2O = 2-Hydroxymuconate + Methanol
[Fig] 5.3.2.- : (Z)-5-Oxohex-2-enedioate = 2-Hydroxymuconate

Reported reactions

[Fig] EC 5.3.3.- : 2-Hydroxymuconate = (Z)-5-Oxohex-2-enedioate
[Fig] EC 1.2.1.32 : 2-Hydroxymuconate semialdehyde + NAD+ + H2O = 2-Hydroxymuconate + NADH
[Fig] EC 3.7.1.8 : 2-Hydroxy-6-oxo-6-(2-hydroxyphenoxy)-hexa-2,4-dienoate + H2O = 2-Hydroxymuconate + 1,2-Benzenediol

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.