GREP C02170

Selected compound(s)

C02170 Methylmalonate

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.2.1.- : (S)-Methylmalonate semialdehyde + H2O + NAD+ = Methylmalonate + NADH + H+
[Fig] 1.2.1.- : (S)-Methylmalonate semialdehyde + H2O + NAD+ = Methylmalonate + NADH + H+
[Fig] 1.2.1.- : (S)-Methylmalonate semialdehyde + H2O + NADP+ = Methylmalonate + NADPH + H+
[Fig] 1.2.1.- : (S)-Methylmalonate semialdehyde + H2O + NADP+ = Methylmalonate + NADPH + H+
[Fig] 1.2.3.- : (S)-Methylmalonate semialdehyde + H2O + O2 = Methylmalonate + H2O2
[Fig] 1.2.3.- : (S)-Methylmalonate semialdehyde + H2O + O2 = Methylmalonate + H2O2
[Fig] 3.1.2.- : (S)-2-Methyl-3-oxopropanoyl-CoA + H2O = CoA + Methylmalonate
[Fig] 3.1.2.- : (R)-2-Methyl-3-oxopropanoyl-CoA + H2O = CoA + Methylmalonate
[Fig] 6.2.1.- : CoA + Methylmalonate + ATP = (S)-2-Methyl-3-oxopropanoyl-CoA + ADP + Orthophosphate
[Fig] 6.2.1.- : CoA + Methylmalonate + ATP = (S)-2-Methyl-3-oxopropanoyl-CoA + Diphosphate + 5'-AMP
[Fig] 6.2.1.- : CoA + Methylmalonate + ATP = (R)-2-Methyl-3-oxopropanoyl-CoA + ADP + Orthophosphate
[Fig] 6.2.1.- : CoA + Methylmalonate + ATP = (R)-2-Methyl-3-oxopropanoyl-CoA + Diphosphate + 5'-AMP

Reported reactions

[Fig] EC 3.5.2.1 : 5-Methylbarbiturate + H2O = Methylmalonate + Carbamide
[Fig] EC 1.2.3.1 : Methylmalonate + O2- = (S)-Methylmalonate semialdehyde + O2 + H2O
[Fig] EC 3.1.2.17 : (S)-2-Methyl-3-oxopropanoyl-CoA + H2O = Methylmalonate + CoA
[Fig] EC 1.2.1.3 : (S)-Methylmalonate semialdehyde + NAD+ + H2O = Methylmalonate + NADH

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.