GREP C01598

Selected compound(s)

C01598 Melatonin

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.14.13.- : 6-Hydroxymelatonin + H2O + NAD+ = Melatonin + NADH + O2 + H+
[Fig] 1.14.13.- : 6-Hydroxymelatonin + H2O + NADP+ = Melatonin + NADPH + O2 + H+
[Fig] 2.1.1.- : N-Acetyl-5-hydroxytryptamine + S-Adenosyl-L-methionine = Melatonin + S-Adenosyl-L-homocysteine
[Fig] 2.1.1.- : N-Acetyl-5-hydroxytryptamine + S-Adenosyl-L-methionine = Melatonin + S-Adenosyl-L-homocysteine + H+
[Fig] 3.3.2.- : Melatonin + H2O = N-Acetyl-5-hydroxytryptamine + Methanol

Reported reactions

[Fig] EC 2.1.1.4 : S-Adenosyl-L-methionine + N-Acetyl-5-hydroxytryptamine = S-Adenosyl-L-homocysteine + Melatonin
[Fig] EC 1.13.11.42 : Melatonin + O2 = Formyl-N-acetyl-5-methoxykynurenamine
[Fig] EC 1.14.14.1 : Melatonin + Reduced flavoprotein + O2 = 6-Hydroxymelatonin + Oxidized flavoprotein + H2O

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.