GREP C01297

Selected compound(s)

C01297 1-(6-Hydroxypyrid-3-yl)-4-(methylamino)butan-1-one

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.14.11.- : (S)-6-Hydroxynicotine + O2 + 2-Ketoglutaric acid = 1-(6-Hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + CO2 + Butanedionic acid
[Fig] 1.14.13.- : 1-(6-Hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + H2O + NAD+ = (S)-6-Hydroxynicotine + NADH + O2 + H+
[Fig] 1.14.13.- : 1-(6-Hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + H2O + NADP+ = (S)-6-Hydroxynicotine + NADPH + O2 + H+
[Fig] 1.14.16.- : 1-(6-Hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + 6,7-Dihydrobiopterin + H2O = (S)-6-Hydroxynicotine + 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + O2
[Fig] 1.14.17.- : (S)-6-Hydroxynicotine + Vitamin C + O2 = 1-(6-Hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + Dehydroascorbate + H2O

Reported reactions

[Fig] EC 1.5.3.5 : (S)-6-Hydroxynicotine + H2O + O2 = 1-(6-Hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + H2O2

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.