GREP C01213

Selected compound(s)

C01213 (R)-2-Methyl-3-oxopropanoyl-CoA

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.1.1.- : 3-Hydroxy-2-methylpropanoyl-CoA + H2O + 2 NAD+ = (R)-2-Methyl-3-oxopropanoyl-CoA + 2 NADH + 2 H+
[Fig] 1.1.1.- : 3-Hydroxy-2-methylpropanoyl-CoA + H2O + 2 NADP+ = (R)-2-Methyl-3-oxopropanoyl-CoA + 2 NADPH + 2 H+
[Fig] 1.1.1.- : 3-Hydroxy-2-methylpropanoyl-CoA + H2O + NAD+ = (R)-2-Methyl-3-oxopropanoyl-CoA + NADH + H+
[Fig] 1.1.1.- : 3-Hydroxy-2-methylpropanoyl-CoA + H2O + NADP+ = (R)-2-Methyl-3-oxopropanoyl-CoA + NADPH + H+
[Fig] 1.1.4.- : 3-Hydroxy-2-methylpropanoyl-CoA + H2O + Oxidized dithiothreitol = (R)-2-Methyl-3-oxopropanoyl-CoA + 1,4-Dithiothreitol
[Fig] 2.1.1.- : Malonyl-CoA + S-Adenosyl-L-methionine = (R)-2-Methyl-3-oxopropanoyl-CoA + S-Adenosyl-L-homocysteine
[Fig] 2.1.1.- : Malonyl-CoA + S-Adenosyl-L-methionine = (R)-2-Methyl-3-oxopropanoyl-CoA + S-Adenosyl-L-homocysteine + H+
[Fig] 2.1.1.- : omega-Carboxyacyl-CoA + S-Adenosyl-L-methionine = (R)-2-Methyl-3-oxopropanoyl-CoA + S-Adenosyl-L-homocysteine
[Fig] 2.1.1.- : omega-Carboxyacyl-CoA + S-Adenosyl-L-methionine = (R)-2-Methyl-3-oxopropanoyl-CoA + S-Adenosyl-L-homocysteine + H+
[Fig] 2.1.2.- : (R)-2-Methyl-3-oxopropanoyl-CoA + THF = Propanoyl-CoA + 10-Formyl-THF
[Fig] 2.1.2.- : (R)-2-Methyl-3-oxopropanoyl-CoA + THF = Long-chain acyl-CoA + 10-Formyl-THF
[Fig] 3.1.2.- : (R)-2-Methyl-3-oxopropanoyl-CoA + H2O = CoA + Methylmalonate
[Fig] 3.3.2.- : (R)-2-Methyl-3-oxopropanoyl-CoA + H2O = Malonyl-CoA + Methanol
[Fig] 3.3.2.- : (R)-2-Methyl-3-oxopropanoyl-CoA + H2O = omega-Carboxyacyl-CoA + Methanol
[Fig] 3.7.1.- : (R)-2-Methyl-3-oxopropanoyl-CoA + H2O = Propanoyl-CoA + Formate
[Fig] 3.7.1.- : (R)-2-Methyl-3-oxopropanoyl-CoA + H2O = Long-chain acyl-CoA + Formate
[Fig] 4.1.1.- : Propanoyl-CoA + CO2 = (R)-2-Methyl-3-oxopropanoyl-CoA
[Fig] 4.1.1.- : Long-chain acyl-CoA + CO2 = (R)-2-Methyl-3-oxopropanoyl-CoA
[Fig] 5.-.-.- : (R)-2-Methyl-3-oxopropanoyl-CoA = (S)-2-Methyl-3-oxopropanoyl-CoA
[Fig] 5.-.-.- : (R)-2-Methyl-3-oxopropanoyl-CoA = 2-Methylmalonyl-CoA
[Fig] 6.2.1.- : CoA + Methylmalonate + ATP = (R)-2-Methyl-3-oxopropanoyl-CoA + ADP + Orthophosphate
[Fig] 6.2.1.- : CoA + Methylmalonate + ATP = (R)-2-Methyl-3-oxopropanoyl-CoA + Diphosphate + 5'-AMP
[Fig] 6.4.1.- : Propanoyl-CoA + ATP + Acid carbonate = (R)-2-Methyl-3-oxopropanoyl-CoA + ADP + Orthophosphate
[Fig] 6.4.1.- : (R)-2-Methyl-3-oxopropanoyl-CoA + ADP + Orthophosphate = Propanoyl-CoA + Formate + ATP
[Fig] 6.4.1.- : (R)-2-Methyl-3-oxopropanoyl-CoA + ADP + Orthophosphate = Long-chain acyl-CoA + Formate + ATP
[Fig] 6.4.1.- : Long-chain acyl-CoA + ATP + Acid carbonate = (R)-2-Methyl-3-oxopropanoyl-CoA + ADP + Orthophosphate

Reported reactions

[Fig] EC 5.4.99.2 : (R)-2-Methyl-3-oxopropanoyl-CoA = Succinyl-CoA
[Fig] EC 1.2.1.18 : (S)-Methylmalonate semialdehyde + CoA + NAD+ = (R)-2-Methyl-3-oxopropanoyl-CoA + NADH
[Fig] EC 5.1.99.1 : (R)-2-Methyl-3-oxopropanoyl-CoA = (S)-2-Methyl-3-oxopropanoyl-CoA

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.