GREP C01147

Selected compound(s)

C01147 2-Hydroxycyclohexan-1-one

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.1.1.- : 2-Hydroxycyclohexan-1-one + NAD+ = Cyclohexan-1,2-dione + NADH + H+
[Fig] 1.1.1.- : 2-Hydroxycyclohexan-1-one + NADPH + H+ = trans-1,2-Cyclohexanediol + NADP+
[Fig] 1.1.1.- : 2-Hydroxycyclohexan-1-one + NADPH + H+ = cis-Cyclohexane-1,2-diol + NADP+
[Fig] 1.1.1.- : 2-Hydroxycyclohexan-1-one + NADPH + H+ = cis-Cyclohexane-1,2-diol + NADP+
[Fig] 1.1.1.- : trans-1,2-Cyclohexanediol + NAD+ = 2-Hydroxycyclohexan-1-one + NADH + H+
[Fig] 1.1.1.- : Cyclohexan-1,2-dione + NADPH + H+ = 2-Hydroxycyclohexan-1-one + NADP+
[Fig] 1.1.1.- : cis-Cyclohexane-1,2-diol + NAD+ = 2-Hydroxycyclohexan-1-one + NADH + H+
[Fig] 1.1.1.- : cis-Cyclohexane-1,2-diol + NAD+ = 2-Hydroxycyclohexan-1-one + NADH + H+
[Fig] 1.1.3.- : 2-Hydroxycyclohexan-1-one + O2 = Cyclohexan-1,2-dione + H2O2
[Fig] 1.1.3.- : trans-1,2-Cyclohexanediol + O2 = 2-Hydroxycyclohexan-1-one + H2O2
[Fig] 1.1.3.- : cis-Cyclohexane-1,2-diol + O2 = 2-Hydroxycyclohexan-1-one + H2O2
[Fig] 1.1.3.- : cis-Cyclohexane-1,2-diol + O2 = 2-Hydroxycyclohexan-1-one + H2O2
[Fig] 1.1.4.- : 2-Hydroxycyclohexan-1-one + 1,4-Dithiothreitol = trans-1,2-Cyclohexanediol + Oxidized dithiothreitol
[Fig] 1.1.4.- : 2-Hydroxycyclohexan-1-one + 1,4-Dithiothreitol = cis-Cyclohexane-1,2-diol + Oxidized dithiothreitol
[Fig] 1.1.4.- : 2-Hydroxycyclohexan-1-one + 1,4-Dithiothreitol = cis-Cyclohexane-1,2-diol + Oxidized dithiothreitol
[Fig] 1.1.4.- : Cyclohexan-1,2-dione + 1,4-Dithiothreitol = 2-Hydroxycyclohexan-1-one + Oxidized dithiothreitol
[Fig] 1.1.5.- : 2-Hydroxycyclohexan-1-one + Reduced thioredoxin = trans-1,2-Cyclohexanediol + Oxidized thioredoxin
[Fig] 1.1.5.- : 2-Hydroxycyclohexan-1-one + Reduced thioredoxin = cis-Cyclohexane-1,2-diol + Oxidized thioredoxin
[Fig] 1.1.5.- : 2-Hydroxycyclohexan-1-one + Reduced thioredoxin = cis-Cyclohexane-1,2-diol + Oxidized thioredoxin
[Fig] 1.1.5.- : 2-Hydroxycyclohexan-1-one + CoQH2 = trans-1,2-Cyclohexanediol + CoQ
[Fig] 1.1.5.- : 2-Hydroxycyclohexan-1-one + CoQH2 = cis-Cyclohexane-1,2-diol + CoQ
[Fig] 1.1.5.- : 2-Hydroxycyclohexan-1-one + CoQH2 = cis-Cyclohexane-1,2-diol + CoQ
[Fig] 1.1.5.- : 2-Hydroxycyclohexan-1-one + Coenzyme F420 = Cyclohexan-1,2-dione + Reduced coenzyme F420
[Fig] 1.1.5.- : trans-1,2-Cyclohexanediol + Coenzyme F420 = 2-Hydroxycyclohexan-1-one + Reduced coenzyme F420
[Fig] 1.1.5.- : Cyclohexan-1,2-dione + Reduced thioredoxin = 2-Hydroxycyclohexan-1-one + Oxidized thioredoxin
[Fig] 1.1.5.- : Cyclohexan-1,2-dione + CoQH2 = 2-Hydroxycyclohexan-1-one + CoQ
[Fig] 1.1.5.- : cis-Cyclohexane-1,2-diol + Coenzyme F420 = 2-Hydroxycyclohexan-1-one + Reduced coenzyme F420
[Fig] 1.1.5.- : cis-Cyclohexane-1,2-diol + Coenzyme F420 = 2-Hydroxycyclohexan-1-one + Reduced coenzyme F420
[Fig] 1.1.99.- : 2-Hydroxycyclohexan-1-one + FAD = Cyclohexan-1,2-dione + FADH2
[Fig] 1.1.99.- : trans-1,2-Cyclohexanediol + FAD = 2-Hydroxycyclohexan-1-one + FADH2
[Fig] 1.1.99.- : cis-Cyclohexane-1,2-diol + FAD = 2-Hydroxycyclohexan-1-one + FADH2
[Fig] 1.1.99.- : cis-Cyclohexane-1,2-diol + FAD = 2-Hydroxycyclohexan-1-one + FADH2
[Fig] 1.14.11.- : 2-Hydroxycyclohexan-1-one + O2 + 2-Ketoglutaric acid = 6-Hydroxyhexan-6-olide + CO2 + Butanedionic acid
[Fig] 1.14.11.- : 2-Hydroxycyclohexan-1-one + O2 + 2-Ketoglutaric acid = Hexan-1-ol-6-oate + CO2 + Butanedionic acid
[Fig] 1.14.11.- : 2-Hydroxycyclohexan-1-one + O2 + 2-Ketoglutaric acid = 1-Oxa-2-oxo-3-hydroxycycloheptane + CO2 + Butanedionic acid
[Fig] 1.14.13.- : 6-Hydroxyhexan-6-olide + H2O + NAD+ = 2-Hydroxycyclohexan-1-one + NADH + O2 + H+
[Fig] 1.14.13.- : 6-Hydroxyhexan-6-olide + H2O + NADP+ = 2-Hydroxycyclohexan-1-one + NADPH + O2 + H+
[Fig] 1.14.13.- : Hexan-1-ol-6-oate + H2O + NAD+ = 2-Hydroxycyclohexan-1-one + NADH + O2 + H+
[Fig] 1.14.13.- : Hexan-1-ol-6-oate + H2O + NADP+ = 2-Hydroxycyclohexan-1-one + NADPH + O2 + H+
[Fig] 1.14.13.- : 1-Oxa-2-oxo-3-hydroxycycloheptane + H2O + NAD+ = 2-Hydroxycyclohexan-1-one + NADH + O2 + H+
[Fig] 1.14.13.- : 1-Oxa-2-oxo-3-hydroxycycloheptane + H2O + NADP+ = 2-Hydroxycyclohexan-1-one + NADPH + O2 + H+
[Fig] 1.14.16.- : 6-Hydroxyhexan-6-olide + 6,7-Dihydrobiopterin + H2O = 2-Hydroxycyclohexan-1-one + 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + O2
[Fig] 1.14.16.- : Hexan-1-ol-6-oate + 6,7-Dihydrobiopterin + H2O = 2-Hydroxycyclohexan-1-one + 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + O2
[Fig] 1.14.16.- : 1-Oxa-2-oxo-3-hydroxycycloheptane + 6,7-Dihydrobiopterin + H2O = 2-Hydroxycyclohexan-1-one + 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + O2
[Fig] 1.14.17.- : 2-Hydroxycyclohexan-1-one + Vitamin C + O2 = 6-Hydroxyhexan-6-olide + Dehydroascorbate + H2O
[Fig] 1.14.17.- : 2-Hydroxycyclohexan-1-one + Vitamin C + O2 = Hexan-1-ol-6-oate + Dehydroascorbate + H2O
[Fig] 1.14.17.- : 2-Hydroxycyclohexan-1-one + Vitamin C + O2 = 1-Oxa-2-oxo-3-hydroxycycloheptane + Dehydroascorbate + H2O

Reported reactions

[Fig] EC 1.1.1.174 : cis-Cyclohexane-1,2-diol + NAD+ = 2-Hydroxycyclohexan-1-one + NADH
[Fig] EC 1.14.13.22 : NADPH + 2-Hydroxycyclohexan-1-one + H+ + O2 = NADP+ + 1-Oxa-2-oxo-3-hydroxycycloheptane + H2O
[Fig] EC 1.1.1.174 : 2-Hydroxycyclohexan-1-one + NAD+ = Cyclohexan-1,2-dione + NADH
[Fig] EC 1.1.1.174 : trans-1,2-Cyclohexanediol + NAD+ = 2-Hydroxycyclohexan-1-one + NADH
[Fig] EC 1.14.13.66 : 2-Hydroxycyclohexan-1-one + O2 + NADPH = 6-Hydroxyhexan-6-olide + NADP+ + H2O

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.