GREP C00674

Selected compound(s)

C00674 5alpha-Androstane-3,17-dione

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.1.1.- : 3alpha-Hydroxy-5alpha-androstan-17-one + NAD+ = 5alpha-Androstane-3,17-dione + NADH + H+
[Fig] 1.1.1.- : 5alpha-Androstane-3,17-dione + NADPH + H+ = 3alpha-Hydroxy-5alpha-androstan-17-one + NADP+
[Fig] 1.1.3.- : 3alpha-Hydroxy-5alpha-androstan-17-one + O2 = 5alpha-Androstane-3,17-dione + H2O2
[Fig] 1.1.4.- : 5alpha-Androstane-3,17-dione + 1,4-Dithiothreitol = 3alpha-Hydroxy-5alpha-androstan-17-one + Oxidized dithiothreitol
[Fig] 1.1.5.- : 3alpha-Hydroxy-5alpha-androstan-17-one + Coenzyme F420 = 5alpha-Androstane-3,17-dione + Reduced coenzyme F420
[Fig] 1.1.5.- : 5alpha-Androstane-3,17-dione + Reduced thioredoxin = 3alpha-Hydroxy-5alpha-androstan-17-one + Oxidized thioredoxin
[Fig] 1.1.5.- : 5alpha-Androstane-3,17-dione + CoQH2 = 3alpha-Hydroxy-5alpha-androstan-17-one + CoQ
[Fig] 1.1.99.- : 3alpha-Hydroxy-5alpha-androstan-17-one + FAD = 5alpha-Androstane-3,17-dione + FADH2
[Fig] 1.3.1.- : 4-Androstene-3,17-dione + NADPH + H+ = 5alpha-Androstane-3,17-dione + NADP+
[Fig] 1.3.1.- : 5alpha-Androstane-3,17-dione + NAD+ = 4-Androstene-3,17-dione + NADH + H+
[Fig] 1.3.3.- : 5alpha-Androstane-3,17-dione + O2 = 4-Androstene-3,17-dione + H2O2
[Fig] 1.3.4.- : 4-Androstene-3,17-dione + 1,4-Dithiothreitol = 5alpha-Androstane-3,17-dione + Oxidized dithiothreitol
[Fig] 1.3.5.- : 4-Androstene-3,17-dione + CoQH2 = 5alpha-Androstane-3,17-dione + CoQ
[Fig] 1.3.99.- : 5alpha-Androstane-3,17-dione + FAD = 4-Androstene-3,17-dione + FADH2
[Fig] 1.3.99.- : 5alpha-Androstane-3,17-dione + Coenzyme F420 = 4-Androstene-3,17-dione + Reduced coenzyme F420
[Fig] 1.14.11.- : 5alpha-Androstane-3,17-dione + O2 + 2-Ketoglutaric acid = 16alpha-Hydroxydehydroepiandrosterone + CO2 + Butanedionic acid
[Fig] 1.14.13.- : 16alpha-Hydroxydehydroepiandrosterone + H2O + NAD+ = 5alpha-Androstane-3,17-dione + NADH + O2 + H+
[Fig] 1.14.13.- : 16alpha-Hydroxydehydroepiandrosterone + H2O + NADP+ = 5alpha-Androstane-3,17-dione + NADPH + O2 + H+
[Fig] 1.14.16.- : 16alpha-Hydroxydehydroepiandrosterone + 6,7-Dihydrobiopterin + H2O = 5alpha-Androstane-3,17-dione + 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + O2
[Fig] 1.14.17.- : 5alpha-Androstane-3,17-dione + Vitamin C + O2 = 16alpha-Hydroxydehydroepiandrosterone + Dehydroascorbate + H2O

Reported reactions

[Fig] EC 1.1.1.50 : 3alpha-Hydroxy-5alpha-androstan-17-one + NAD+ = 5alpha-Androstane-3,17-dione + NADH
[Fig] EC 1.1.1.209 : 3alpha-Hydroxy-5alpha-androstan-17-one + NAD+ = 5alpha-Androstane-3,17-dione + NADH
[Fig] EC 1.1.1.213 : 3alpha-Hydroxy-5alpha-androstan-17-one + NAD+ = 5alpha-Androstane-3,17-dione + NADH
[Fig] EC 1.1.1.50 : 3alpha-Hydroxy-5alpha-androstan-17-one + NADP+ = 5alpha-Androstane-3,17-dione + NADPH
[Fig] EC 1.1.1.209 : 3alpha-Hydroxy-5alpha-androstan-17-one + NADP+ = 5alpha-Androstane-3,17-dione + NADPH
[Fig] EC 1.1.1.213 : 3alpha-Hydroxy-5alpha-androstan-17-one + NADP+ = 5alpha-Androstane-3,17-dione + NADPH
[Fig] EC 1.3.99.5 : 5alpha-Androstane-3,17-dione + Acceptor = 4-Androstene-3,17-dione + Reduced acceptor

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.