GREP C00643

Selected compound(s)

C00643 5-Hydroxy-L-tryptophan

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.4.1.- : 5-Hydroxy-L-tryptophan + H2O + NAD+ = 5-Hydroxyindolepyruvate + NADH + Ammonia
[Fig] 1.4.1.- : 5-Hydroxy-L-tryptophan + H2O + NAD+ = 5-Hydroxyindolepyruvate + NADH + Ammonia + H+
[Fig] 1.4.1.- : 5-Hydroxy-L-tryptophan + H2O + NAD+ = 5-Hydroxyindolepyruvate + NADH + H+ + Ammonia
[Fig] 1.4.1.- : 5-Hydroxy-L-tryptophan + H2O + NADP+ = 5-Hydroxyindolepyruvate + NADPH + Ammonia
[Fig] 1.4.1.- : 5-Hydroxy-L-tryptophan + H2O + NADP+ = 5-Hydroxyindolepyruvate + NADPH + Ammonia + H+
[Fig] 1.4.1.- : 5-Hydroxy-L-tryptophan + H2O + NADP+ = 5-Hydroxyindolepyruvate + NADPH + H+ + Ammonia
[Fig] 1.4.1.- : 5-Hydroxy-L-tryptophan + NAD+ + H2O = 5-Hydroxyindolepyruvate + Ammonia + NADH
[Fig] 1.4.1.- : 5-Hydroxy-L-tryptophan + NAD+ + H2O = 5-Hydroxyindolepyruvate + Ammonia + NADH + H+
[Fig] 1.4.1.- : 5-Hydroxy-L-tryptophan + NADP+ + H2O = 5-Hydroxyindolepyruvate + Ammonia + NADPH
[Fig] 1.4.1.- : 5-Hydroxy-L-tryptophan + NADP+ + H2O = 5-Hydroxyindolepyruvate + Ammonia + NADPH + H+
[Fig] 1.4.3.- : 5-Hydroxy-L-tryptophan + H2O + O2 = 5-Hydroxyindolepyruvate + Ammonia + H2O2
[Fig] 1.14.13.- : 5-Hydroxy-L-tryptophan + H2O + NAD+ = L-Tryptophan + NADH + O2 + H+
[Fig] 1.14.13.- : 5-Hydroxy-L-tryptophan + H2O + NADP+ = L-Tryptophan + NADPH + O2 + H+
[Fig] 2.1.2.- : 5-Hydroxy-L-tryptophan + THF = 3-(2-Aminoethyl)-1H-indol-5-ol + 10-Formyl-THF
[Fig] 2.6.1.- : 5-Hydroxy-L-tryptophan + Pyridoxal 5'-phosphate = 5-Hydroxyindolepyruvate + Pyridoxamine 5'-phosphate
[Fig] 2.6.1.- : 5-Hydroxyindolepyruvate + L-Glutamate = 5-Hydroxy-L-tryptophan + 2-Ketoglutaric acid
[Fig] 3.7.1.- : 5-Hydroxy-L-tryptophan + H2O = 3-(2-Aminoethyl)-1H-indol-5-ol + Formate
[Fig] 4.1.1.- : 3-(2-Aminoethyl)-1H-indol-5-ol + CO2 = 5-Hydroxy-L-tryptophan
[Fig] 6.4.1.- : 5-Hydroxy-L-tryptophan + ADP + Orthophosphate = 3-(2-Aminoethyl)-1H-indol-5-ol + Formate + ATP
[Fig] 6.4.1.- : 3-(2-Aminoethyl)-1H-indol-5-ol + ATP + Acid carbonate = 5-Hydroxy-L-tryptophan + ADP + Orthophosphate

Reported reactions

[Fig] EC 2.6.1.27 : 5-Hydroxy-L-tryptophan + 2-Ketoglutaric acid = 5-Hydroxyindolepyruvate + L-Glutamate
[Fig] EC 4.1.1.28 : 5-Hydroxy-L-tryptophan = 3-(2-Aminoethyl)-1H-indol-5-ol + CO2
[Fig] EC 1.13.11.42 : 5-Hydroxy-L-tryptophan + O2 = 5-Hydroxy-N-formylkynurenine
[Fig] EC 1.14.16.4 : 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydoro-4(1H)- pteridinone + L-Tryptophan + O2 = 5-Hydroxy-L-tryptophan + 6,7-Dihydrobiopterin + H2O

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.