GREP C00487

Selected compound(s)

C00487 3-Hydroxy-4-trimethylammoniobutanoate

Each orphan metabolite is emphasized in bold. Click [Fig] on the left hand, and the image of the reaction is shown.
[Suggested reactions | Reported reactions]

Suggested reactions

[Fig] 1.1.1.- : 3-Hydroxy-4-trimethylammoniobutanoate + NAD+ = 3-Carboxy-N,N,N-trimethyl-2-oxo-1-propanaminium + NADH + H+
[Fig] 1.1.1.- : 3-Carboxy-N,N,N-trimethyl-2-oxo-1-propanaminium + NADPH + H+ = 3-Hydroxy-4-trimethylammoniobutanoate + NADP+
[Fig] 1.1.3.- : 3-Hydroxy-4-trimethylammoniobutanoate + O2 = 3-Carboxy-N,N,N-trimethyl-2-oxo-1-propanaminium + H2O2
[Fig] 1.1.4.- : 3-Carboxy-N,N,N-trimethyl-2-oxo-1-propanaminium + 1,4-Dithiothreitol = 3-Hydroxy-4-trimethylammoniobutanoate + Oxidized dithiothreitol
[Fig] 1.1.5.- : 3-Hydroxy-4-trimethylammoniobutanoate + Coenzyme F420 = 3-Carboxy-N,N,N-trimethyl-2-oxo-1-propanaminium + Reduced coenzyme F420
[Fig] 1.1.5.- : 3-Carboxy-N,N,N-trimethyl-2-oxo-1-propanaminium + Reduced thioredoxin = 3-Hydroxy-4-trimethylammoniobutanoate + Oxidized thioredoxin
[Fig] 1.1.5.- : 3-Carboxy-N,N,N-trimethyl-2-oxo-1-propanaminium + CoQH2 = 3-Hydroxy-4-trimethylammoniobutanoate + CoQ
[Fig] 1.1.99.- : 3-Hydroxy-4-trimethylammoniobutanoate + FAD = 3-Carboxy-N,N,N-trimethyl-2-oxo-1-propanaminium + FADH2
[Fig] 1.14.11.- : 4-Trimethylammoniobutanoate + O2 + 2-Ketoglutaric acid = 3-Hydroxy-4-trimethylammoniobutanoate + CO2 + Butanedionic acid
[Fig] 2.1.2.- : 3-Hydroxy-4-trimethylammoniobutanoate + THF = 2-Methylcholine + 10-Formyl-THF
[Fig] 2.3.1.- : O-Acetyl-L-carnitine + CoA = 3-Hydroxy-4-trimethylammoniobutanoate + Acetyl-CoA
[Fig] 3.1.1.- : O-Acetyl-L-carnitine + H2O = 3-Hydroxy-4-trimethylammoniobutanoate + Acetate
[Fig] 3.7.1.- : 3-Hydroxy-4-trimethylammoniobutanoate + H2O = 2-Methylcholine + Formate
[Fig] 4.1.1.- : 2-Methylcholine + CO2 = 3-Hydroxy-4-trimethylammoniobutanoate
[Fig] 4.1.3.- : Betaine aldehyde + Acetate = 3-Hydroxy-4-trimethylammoniobutanoate
[Fig] 6.4.1.- : 3-Hydroxy-4-trimethylammoniobutanoate + ADP + Orthophosphate = 2-Methylcholine + Formate + ATP
[Fig] 6.4.1.- : 2-Methylcholine + ATP + Acid carbonate = 3-Hydroxy-4-trimethylammoniobutanoate + ADP + Orthophosphate

Reported reactions

[Fig] EC 1.1.1.108 : 3-Hydroxy-4-trimethylammoniobutanoate + NAD+ = 3-Carboxy-N,N,N-trimethyl-2-oxo-1-propanaminium + NADH + H+
[Fig] EC 2.3.1.7 : Acetyl-CoA + 3-Hydroxy-4-trimethylammoniobutanoate = CoA + O-Acetyl-L-carnitine
[Fig] EC 1.14.11.1 : 4-Trimethylammoniobutanoate + 2-Ketoglutaric acid + O2 = 3-Hydroxy-4-trimethylammoniobutanoate + Butanedionic acid + CO2
[Fig] EC 4.1.1.42 : 3-Hydroxy-4-trimethylammoniobutanoate = 2-Methylcholine + CO2
[Fig] EC 1.14.11.1 : 3-Dehydroxycarnitine = 3-Hydroxy-4-trimethylammoniobutanoate

GREP v1.0.2 http://bisscat.org/GREP/
Developed by Masaaki Kotera (2008), Department of Biochemistry, Trinity College Dublin.
Science Foundation of Ireland is gratefully acknowledged.